70933-58-3Relevant articles and documents
INHIBITORS OF HEPATITIS C VIRUS REPLICATION
-
Paragraph 0810-0811, (2019/05/15)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
A to aryl diazonium tetrafluoroborate salts with a nitrile preparation machine acid radical amine compounds (by machine translation)
-
Paragraph 0040, (2018/06/04)
The invention provides a high-efficiency, high-selective synthesis of different substituted functional group containing organic amide compound, it adopts the cuprous iodide as a catalyst, in order to aryl diazonium tetrafluoroborate salts compounds and organic nitrile compound as the reaction substrate, the reaction system by adding the organic solvent, water and alkali. The advantage of this method: cheap and easily obtained catalyst; the substrate has a high applicability; mild reaction conditions, safe and reliable; the resulting target product selectivity is close to 100%, yield is as high as 90% or more. The method solves the traditional synthetic organic amide compound of rigorous reaction conditions, the reaction selectivity is poor, the experimental procedure is complicated, the productivity is low and needs to be used for the environment of a harmful reagent and the like, it has good industrial application prospect. The invention also provides a corresponding different substituted functional group containing organic amide compound. (by machine translation)
Synthesis of N = 8 Armchair Graphene Nanoribbons from Four Distinct Polydiacetylenes
Jordan, Robert S.,Li, Yolanda L.,Lin, Cheng-Wei,McCurdy, Ryan D.,Lin, Janice B.,Brosmer, Jonathan L.,Marsh, Kristofer L.,Khan, Saeed I.,Houk,Kaner, Richard B.,Rubin, Yves
supporting information, p. 15878 - 15890 (2017/11/14)
We demonstrate a highly efficient thermal conversion of four differently substituted polydiacetylenes (PDAs 1 and 2a-c) into virtually indistinguishable N = 8 armchair graphene nanoribbons ([8]AGNR). PDAs 1 and 2a-c are themselves easily access