70941-73-0Relevant articles and documents
Iodosulfonation of alkenes with benzenesulfinic acid - N-iodosuccinimide - Facile preparation of αβ-unsaturated sulfones
Wolff, Russell R.,Basava, Vikram,Giuliano, Robert M.,Boyko, Walter J.,Schauble, J. Herman
, p. 667 - 675 (2007/10/03)
Reaction of alkenes and alkenols with N-iodosuccinimide (NIS) and benzenesulfinic acid in dichloromethane at room temperature affords vic-iodophenylsulfonyl adducts in good to high yields. Treatment of the iodosulfones with neutral alumina in dichlorometh
7-Oxanorbornane and norbornane mimics of a distorted β-D- mannopyranoside: Synthesis and evaluation as β-mannosidase inhibitors
Buser, Stephan,Vasella, Andrea
, p. 3151 - 3173 (2007/10/03)
The racemic 7-oxanorbornanyl and norbornanyl aminoalcohols 3, 4, 42, 45, and 46 were synthesized and tested as snail β-mannosidase inhibitors. The amino tetraol 3 was obtained from the known sulfonyl acrylate 9 and furan 10. Esterification provided 11 tha
Homochiral oxazolidin-2-ones and imidazolidin-2-ones by tandem nucleophilic addition-conjugate addition
Ciclosi, Marco,Fava, Cristiana,Galeazzi, Roberta,Orena, Mario,Gonzalez-Rosende, Maria Eugenia,Sepulveda-Arques, Jose
, p. 1937 - 1943 (2007/10/03)
Treatment of both primary alcohols 1a,b and secondary amines 1c,d, tethered to a Michael acceptor with (R)-phenylethyl isocyanate in the presence of DBU gave in good yield and high stereoselection diastereomeric mixtures of oxazolidin-2-ones 2a,b and 3a,b
Stereoselective synthesis of trans-4,5-disubstituted oxazolidin-2-ones by intramolecular conjugate addition of N-p-toluenesulfonyl carbamates
Ciclosi, Marco,Fava, Cristiana,Galeazzi, Roberta,Orena, Mario,Sepúlveda-Arques, José,González-Rosende, Maria Eugenia
, p. 1173 - 1183 (2007/10/03)
p-Toluenesulfonyl carbamates (2a-d) were prepared starting from allylic alcohols (3), in which the double bond is conjugated with an electron withdrawing group. In the presence of a catalytic amount of DBU, an intramolecular cyclisation occurred, leading
A facile regio- and stereocontrolled synthesis of (E)-disubstituted vinyl sulfones via transformation of alkenylzirconocenes with sulfonyl chlorides
Duan, De-Hui,Huang, Xian
, p. 317 - 318 (2007/10/03)
Alkenylzirconium reagents, readily obtained by hydrozirconation of terminal alkynes, can smoothly react with sulfonyl chlorides to afford (E)- disubstituted vinyl sulfones in moderate to good yields. Some γ- functionalized vinyl sulfones can be also conve
Palladium- and light-enhanced ring-opening of oxiranes by copper chloride
Muzart, Jacques,Riahi, Abdelkhalek
, p. 323 - 336 (2007/10/02)
The yields of chlorohydrins formed by cleavage of epoxides by CuCl2 is increased in the presence of small amounts of PdCl2(MeCN)2.The conversion drops dramatically on carrying out the reaction in the dark.The regiochemistry of the ring-opening is sensitive to the nature of the substituents.
Phenylsulphonyloxiranes as Functional Acyl Anion Equivalents in Organic Synthesis
Ashwell, Mark,Clegg, William,Jackson, Richard F. W.
, p. 897 - 908 (2007/10/02)
Phenylsulphonyloxiranes can be lithiated with butyllithium α to the phenylsulphonyl group at low temperature.The anions formed are unstable, but sufficiently reactive to allow the isolation of adducts in good yield following treatment with a variety of el
