70958-19-9

Usage

Uses

Used in Agricultural Applications:
2-(5-chloro-2-phenoxyphenyl)-1-Morpholinoethanethione is used as an insecticide for the protection of crops against a broad spectrum of pests. Its effectiveness is due to its ability to target the nervous system of insects, such as flies and beetles, leading to their paralysis and death. This makes it a valuable tool in ensuring the health and yield of agricultural produce.
Used in Pest Control:
In the pest control industry, 2-(5-chloro-2-phenoxyphenyl)-1-Morpholinoethanethione is used as a key component in various formulations designed to manage and eliminate insect infestations. Its mode of action, which involves the disruption of the insect nervous system, ensures that it is a potent and reliable option for controlling a wide range of crop-damaging insects.

Upstream product

• 70958-18-8 5-chloro-2-phenoxyacetophenone 
• 108-95-2 phenol 
• 2476-37-1 2,5-dichloroacetophenone 
• 110-91-8 morpholine 
• 139-02-6 sodium phenoxide 

Downstream Products

• 70958-20-2 5-chloro-2-phenoxyphenylacetic acid 

Relevant academic research and scientific papers

Substituted (2-Phenoxyphenyl)acetic Acids with Antiinflammatory Activity. 1

The synthesis and antiinflammatory activity of a series of substituted (2-phenoxyphenyl)acetic acids are described.Initial screening in the adjuvant arthritis test showed that halogen substitution in the phenoxy ring enhanced activity considerably.Ulcerogenic potential, as measured by the minimum ulcerogenic dose (MUD), was low in almost all the acids tested. acetic acid possessed the most favorable combination of potency with low toxicity, including ulcerogenicity, and this compound is now in therapeutic use.

Affinity of 10-(4-Methylpiperazino)dibenzoxepins for Clozapine and Spiroperidol Binding Sites in Rat Brain

10-(4-Methylpiperazino)dibenzoxepins were prepared and evaluated as potential antipsychotic agents using specific clozapine diazepine> binding sites in rat forebrain that are noncholinergic and nondopaminergic in nature and from which clozapine is displaced by known antipsychotic agents. Clozapine binding in the presence of atropine represents nonmuscarinic binding, while binding in the absence of atropine represents muscarinic (cholinergic) plus nonmuscarinic binding.The relative affinity for dopamine binding sites was determined by displacement of spiroperidol from binding sites in rat caudate nuclei.Thus, clozapine, its 2-chloro isomer, its dechloro analogue, and their 5H-dibenzocycloheptene and dibenzoxepin analogues have about the same relative affinity for the nonmuscarinic clozapine binding sites.At the spiroperidol (dopaminergic) sites, both the nature of the tricyclic system and the presence of chlorine atom on the tricyclic system have a substantial effect on the binding affinity.Within each series, shift of a chlorine atom from the position distal to the piperazino group to the proximal position increases the binding affinity by a factor of about nine, but removal of the chlorine atom substantially decreases the binding affinity.Nevertheless, 10-(4-methylpiperazino)dibenzoxepin has a threefold greater affinity for the dopaminergic binding sites than does clozapine itself.

Coated 1-(2-chlorodibenzo[b,f]oxepin-10-yl)-4-methylpiperazine compositions

A coated 1-(2-chlorodibenzo[b,f]oxepin-10-yl)-4-methylpiperazine composition, suitable for pharmaceutical use.