71002-59-0

Basic information

• Product Name: 3-Guanylic acid, 2-deoxy-N-(2-methyl-1-oxopropyl)-, 4-chlorophenyl 2-cyanoethyl ester
• Synonyms: 2'-deoxy-N-(2-methyl-1-oxopropyl)-3'-guanylic acid, 4-chlorophenyl 2-cyanoethyl ester;Phosphoric acid 4-chloro-phenyl ester 2-cyano-ethyl ester (2R,3S,5R)-2-hydroxymethyl-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester
• CAS NO: 71002-59-0
• Molecular Formula: C23H26ClN6O8P
• Molecular Weight: 580.922
• Mol File: 71002-59-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Guanylic acid, 2-deoxy-N-(2-methyl-1-oxopropyl)-, 4-chlorophenyl 2-cyanoethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Guanylic acid, 2-deoxy-N-(2-methyl-1-oxopropyl)-, 4-chlorophenyl 2-cyanoethyl ester(71002-59-0)
• EPA Substance Registry System: 3-Guanylic acid, 2-deoxy-N-(2-methyl-1-oxopropyl)-, 4-chlorophenyl 2-cyanoethyl ester(71002-59-0)

Safety Data

• Hazardous Substances Data: 71002-59-0(Hazardous Substances Data)

Upstream product

• 69507-62-6 (p-chlorophenyl) (β-cyanoethyl) phosphorochloridate 
• 772-79-2 4-chlorophenylphosphorodichloridate 
• 106-48-9 4-chloro-phenol 
• 76742-75-1 5'-O-monomethoxytrityl-N-isobutyryldeoxyguanosine 3'-p-chlorophenylphosphonate 
• 13388-88-0 4-chlorophenyl phosphate 
• 68892-41-1 5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine 
• 71100-72-6 5'-O-(dimethoxytrityl)-N-isobutyrylguanine 3'-(p-chlorophenylcyanoethyl phosphate) 
• 63660-22-0 Phosphoric acid 4-chloro-phenyl ester 2-cyano-ethyl ester (2R,3S,5R)-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 

Downstream Products

• 81551-80-6 C₄₃H₄₇Cl₂N₁₁O₁₅P₂ 
• 90827-16-0 C₃₉H₄₂Cl₂N₈O₁₅P₂ 
• 69924-11-4 C₆₄H₆₅Cl₂N₁₁O₁₇P₂ 
• 73591-24-9 5'-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(4-chlorophenyl)thymidylyl-(3'->5')-2'-deoxy-N-(2-methyl-1-oxopropyl)-3'-guanylic acid, 4-chlorophenyl 2-cyanoethyl ester 

Relevant articles and documents

Synthesis of Deoxyoligonucleotide Linker Fragments for Genetic Engineering Using Improved Preparative and Analytical Techniques

For studies on the expression of recombinant DNA, linker fragments have been prepared which serve to introduce specific points of cleavage on the DNA as well as the protein level.Such linkers were designed for cyanogen bromide as well as for collagenase cleavage of fused proteins.The preparation was done according to the triester synthesis scheme using improved and simpler routes to functionalized dinucleotide building blocks.Field desorption mass spectrometry was used as a routine tool for the identification and control of the purity of these units.