711-90-0Relevant academic research and scientific papers
Decarboxylative Oxyacyloxylation of Propiolic Acids: Construction of Alkynyl-Containing α-Acyloxy Ketones
Chen, Xin,Xin, Yangchun,Zhao, Zhi-Wei,Hou, Yu-Jian,Wang, Xiang-Xiang,Xia, Wen-Jin,Li, Ya-Min
, p. 8216 - 8225 (2021/06/28)
Novel decarboxylative oxyacyloxylation of propiolic acids has been developed. This reaction provides an efficient access to alkynyl-containing α-acyloxy ketones from readily available starting materials and exhibits significant functional group tolerance. Furthermore, oxyacyloxylation of terminal alkynes and aliphatic propiolic acids was also developed. A possible reaction mechanism is proposed based on mechanistic studies.
Sulfur-mediated difunctionalization of internal and terminal alkynes for the synthesis of α-acetoxy ketones
Li, Pingfan,Zhang, Zhong
, (2020/02/13)
The sulfur-mediated difunctionalization of alkynes is reported to give α-acetoxy ketones in a one-pot operation under mild conditions with 19–92% yield. By using wet potassium acetate as both the aqueous base and nucleophilic reagent, both terminal alkynes and internal alkynes could be converted into the α-acetoxy ketone products.
Synthesis of α-hydroxyacetophenones
McLaughlin, Mark,Belyk, Kevin M.,Qian, Gang,Reamer, Robert A.,Chen, Cheng-Yi
experimental part, p. 5144 - 5148 (2012/07/03)
A general method for the preparation of α-hydroxyacetophenones is presented. Functionalized arylmagnesium species are transmetalated to the corresponding arylzinc intermediates, which undergo Cu(I)-catalyzed reaction with acetoxyacetyl chloride. Acidic hy
Copper(II) and 2,2'-biimidazole-promoted novel reaction of 4,4,4-trifluoro-1-phenylbutane-1,3-diones with iodobenzene diacetate
Zhou, Chunmei,Zeng, Runsheng,Zou, Jianping
experimental part, p. 294 - 298 (2010/10/21)
A new and efficient way was developed to carry out the reaction of 4,4,4-trifluoro-1-phenylbutane-1,3-dione with iodobenzene diacetate under the assistance of Cu(II) and 2,2'-biimidazole at a low temperature in excellent yield. 2-Acetoxyacetophenone was obtained unexpectedly.
