71114-52-8

Usage

InChI:InChI=1/C15H15NO/c1-11-8-9-12(2)14(10-11)16-15(17)13-6-4-3-5-7-13/h3-10H,1-2H3,(H,16,17)

Upstream product

• 95-72-7 2-chloro-1,4-dimethyl-benzene 
• 55-21-0 benzamide 
• 98-88-4 benzoyl chloride 
• 108-44-1 1-amino-3-methylbenzene 
• 582-77-4 3'-methylbenzanilide 
• 112359-25-8 5-(trifluoromethyl)dibenzothiophenium trifluoromethanesulfonate 
• 30897-86-0 2,5-dimethylphenylmagnesium bromide 
• 357159-11-6 1-(2,5-dimethylphenyl)-1H-tetrazole 
• 100-52-7 benzaldehyde 
• 95-78-3 2,5-Dimethylaniline 

Downstream Products

• 1383797-00-9 7-methyl-2-phenyl-4H-benzo[d][1,3]oxazine 
• 66354-87-8 6-methyl-2-phenyl-1H-indole 
• 31684-75-0 4-benzoyl-2,5-dimethylaniline 
• 25798-65-6 4,7-dimethyl-2-phenyl-1H-benzo[d]imidazole 
• 117125-10-7 1-(2,5-dimethylphenyl)-6-hydroxy-2-phenylbenzimidazole 
• 117124-93-3 N'-(2,5-dimethylphenyl)-N-(4-hydroxyphenyl)benzenecarboximidamide 
• 117125-01-6 4-imino-2,5-cyclohexadien-1-one 
• 60065-95-4 N-(2,5-dimethylphenyl)benzenecarboximidoyl chloride 
• 115037-70-2 1-benzoylamino-2,5-dimethyl-4-(4-nitro-benzoylamino)-benzene 
• 698-24-8 6-methyl-1H-indazole 

Relevant academic research and scientific papers

Iron-catalysed radical cyclization to synthesize germanium-substituted indolo[2,1-a]isoquinolin-6(5H)-ones and indolin-2-ones

A simple and efficient strategy for iron-catalysed cascade radical cyclization was developed, by which an array of germanium-substituted indolo[2,1-a]isoquinolin-6(5H)-ones and indolin-2-ones were obtained in one pot with germanium hydrides as radical precursors. A rapid intramolecular radical trapping mode enabled the selective arylgermylation of alkenes over the prevalent hydrogermylation reaction.

Sulfonium Salts as Alkylating Agents for Palladium-Catalyzed Direct Ortho Alkylation of Anilides and Aromatic Ureas

A novel method for the ortho alkylation of acetanilide and aromatic urea derivatives via C-H activation was developed. Alkyl dibenzothiophenium salts are considered to be new reagents for the palladium-catalyzed C-H activation reaction, which enables the transfer of methyl and other alkyl groups from the sulfonium salt to the aniline derivatives under mild catalytic conditions.

High yielding electrophilic amination method for arylcopper reagents

The facilitative effect of some P-, N-, S-, and O-donor ligands in the reaction of arylcoppers with acetone O-(mesitylenesulfonyl)oxime was examined to develop a synthesis method for functionalized primary aryl amines under mild reaction conditions. Our research showed that electrophilic amination of monoaryl coppers with ketoximes can be facilitated using appropriate ligand to supply significant increase in the yield. Also, we have seen that this ligand-facilitated method is applicable in terms of arylcopper and ketoxime type and allows synthesis of primary aryl amines in good to high yields easily at room temperature in very short reaction time.

Aryl C-N bond formation by electrophilic amination of diarylcadmium reagents with O-substituted ketoximes

Diorganocadmium reagents cannot react with ketoxime at room temperature. CuCN catalysis allows diarylcadmium reagents to react with ketoxime and to give corresponding arylamines in good to high yields at room temperature. According to the electronic effects of the substituent attached to the aromatic ring, functionalized diarylcadmium reagents show meta-para selectivity in their amination reactions. Also compared to diarylzinc reagents, diarylcadmium reagents react with O-substituted ketoxime under milder reaction conditions and they form corresponding arylamines in higher yields. CuCN cannot help dialkyl-, dicycloalky-, and dibenzylcadmium reagents to react with ketoxime. Our Aryl C-N bond formation method does not include cadmium excretion into the environment.

BENZOYLPHENYL-FORMAMIDINES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE USE

New benzoylphenyl-formamidines having general formula (I): (I) fungicidal compositions containing them, and their use for the control of phytopathogenic fungi of agricultural crops, are described.

Synthesis of amides through an oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions

A simple, inexpensive and efficient one-pot synthesis of amides was achieved in good yields via the direct oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions.

Copper-catalyzed selective benzylic C-O cyclization of N-o-tolylbenzamides: Synthesis of 4 H-3,1-benzoxazines

A novel Selectfluor-mediated copper-catalyzed highly selective benzylic C-O cyclization for the synthesis 4H-3,1-benzoxazines is reported. The predominant selectivity for a benzylic C(sp3)-H over an aromatic C(sp 2)-H bond in N-o-tolylbenzamides is achieved.

Highly efficient catalytic system for electrophilic amination of arylzinc reagents

The effect of catalyst on the yield of amine in the amination of three classes of arylzinc reagents with acetone oxime O-tosylate was investigated. Since they allowed the preparation of arylamines in excellent yields in the presence of a minimum amount of copper (I) or copper (II) compounds, the catalytic systems using copper (I) or copper (II) combined with a P-, N- or S-donor ligand were revealed to be the best catalysts for the electrophilic amination of arylzinc reagents with acetone oxime O-tosylate in the presence of DMPU. Copyright

An efficient system for the Pd-catalyzed cross-coupling of amides and aryl chlorides

A catalyst based on a new biarylphosphine ligand (3) for the Pd-catalyzed cross-coupling reactions of amides and aryl chlorides is described. This system shows the highest turnover frequencies reported to date for these reactions, especially for aryl chloride substrates bearing an ortho substituent. An array of amides and aryl chlorides were successfully reacted in good to excellent yields.