71298-04-9

Upstream product

• 590-50-1 4,4-dimethyl-pentan-2-one 
• 98-88-4 benzoyl chloride 
• 93-89-0 benzoic acid ethyl ester 
• 1070-83-3 tert-Butylacetic acid 
• 98-86-2 acetophenone 
• 71-43-2 benzene 
• 7065-46-5 3,3-dimethylbutanoic acid chloride 
• 55889-34-4 1-(1H-1,2,3-benzotriazol-1-yl)-3,3-dimethyl-1-butanone 
• 957049-08-0 3,3-dimethylbutyric acid pentafluorophenyl ester 

Relevant academic research and scientific papers

Trifluoroacetic Anhydride as an Activator in the Acylation of Aryl Methyl Ketones with Carboxylic Acids

Abstract: Trifluoroacetic anhydride was used as an efficient activator of the acylation of aryl methyl ketones with carboxylic acids in the presence of Br?nsted and Lewis acids (SF3SO3H, MeSO3H, 4-MeC6H4/s

Pyrazoles: 'one-pot' synthesis from arenes and carboxylic acids

A rapid and efficient method for 'one-pot' synthesis of pyrazoles from (hetero)arenes and carboxylic acids via successive formation of ketones and β-diketones followed by heterocyclization with hydrazine has been developed. The utility of the RCOOH/TfOH/TFAA acylation system for intermediate production of ketones and 1,3-diketones is a key feature of this approach. The preliminary evaluation of the anticancer activity of the synthesized pyrazoles is performed.

Synthesis of 1,3-Diketones and β-Keto Thioesters via Soft Enolization

Ketones and thioesters undergo soft enolization and acylation using crude acid chlorides on treatment with MgBr2·OEt2 and i-Pr2NEt to give 1,3-diketones and β-keto thioesters, respectively. The use of crude acid chlorides adds efficiency and cost reduction by avoiding the need to purify and/or purchase them. The process is conducted in a direct fashion that does not require prior enolate formation, further enhancing its efficiency and making it very easy to carry out. The method is suitable for large scale applications. ?

ORGANOMETALLIC COMPLEX, LIGHT EMITTING ELEMENT, LIGHT EMISSION DEVICE, ELECTRONIC APPARATUS, AND ILLUMINATION DEVICE

PROBLEM TO BE SOLVED: To provide an organometallic complex which can convert a triplet excited state to light emission. SOLUTION: The present invention provides an organometallic complex having a structure represented by general formula (G7) where R1 is a branched alkyl group having carbon atoms of 4 or more with straight chain carbon atoms of 3 or more, or an alkyl group having carbon atoms of 5-10, R2 is hydrogen, an alkyl group having carbon atoms of 1-6, or a phenyl group, R3 is hydrogen or an alkyl group having carbon atoms of 1-6, R4-R7 are independently hydrogen, an alkyl group having carbon atoms of 1-6, an alkoxy group having carbon atoms of 1-6, an alkylthio group having carbon atoms of 1-6, a halogen group, a haloalkyl group having carbon atoms of 1-6, or an aryl group having carbon atoms of 1-6, M is central metal and represents a group 9 element or a group 10 element. COPYRIGHT: (C)2015,JPOandINPIT

MgBr2·OEt2-promoted coupling of ketones and activated acyl donors via soft enolization: A practical synthesis of 1,3-diketones

Ketones undergo soft enolization and acylation on treatment with MgBr 2OEt2, i-Pr2NEt, and various acylating agents to give 1,3-diketones. The process is particularly efficient for N-acylbenzotriazoles and O-pentafluorophenyl esters, and, in these cases, is conducted using untreated, reagent grade CH2C12 open to the air, thus providing an exceptionally simple approach to the synthesis of this important class of compounds. Thieme Stuttgart.

Direct carbon - Carbon bond formation via soft enolization: A facile and efficient synthesis of 1,3-diketones

Ketones undergo soft enolate formation and acylation on treatment with MgBr2·OEt2, i-Pr2NEt, and various acylating agents to give 1,3-diketones. The process is particularly efficient for N-acylbenzotriazoles and O-Pfp esters, and, in these cases, is conducted with untreated, reagent-grade CH2Cl2 open to the air, thus providing an exceptionally simple approach to the synthesis of this important class of compounds.