713134-72-6

Basic information

• Product Name: Methyl (R)-(benzhydrylsulfinyl)acetate
• Synonyms: (R)-Modafinil Carboxylate Methyl Ester;2-[(R)-(Diphenylmethyl)sulfinyl]-acetic Acid Methyl Ester;Methyl (R)-(benzhydrylsulfinyl)acetate;R-Methyl, 2-(Benzhydryl sulfinyl) acetate;Acetic acid, [(R)-(diphenylMethyl)sulfinyl]-, Methyl ester (9CI);ArModafinil InterMediate;methl,R-(benzhydryl sulfinyl)acetic acid;Acetic acid,2-[(R)-(diphenylmethyl)sulfinyl]-, methyl ester
• CAS NO: 713134-72-6
• Molecular Formula: C₁₆H₁₆O₃S
• Molecular Weight: 288.36
• Product Categories: Aromatics;Chiral Reagents;Drug Analogues;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
• Mol File: 713134-72-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 483.787 °C at 760 mmHg
• Flash Point: 246.386 °C
• Appearance: Off-White Solid
• Density: 1.242 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.607
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl (R)-(benzhydrylsulfinyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl (R)-(benzhydrylsulfinyl)acetate(713134-72-6)
• EPA Substance Registry System: Methyl (R)-(benzhydrylsulfinyl)acetate(713134-72-6)

Safety Data

• Hazardous Substances Data: 713134-72-6(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

InChI:InChI=1/C16H16O3S/c1-19-15(17)12-20(18)16(13-8-4-2-5-9-13)14-10-6-3-7-11-14/h2-11,16H,12H2,1H3/t20-/m1/s1

Upstream product

• 776-74-9 Bromodiphenylmethane 
• 118286-24-1 methyl diphenylmethylmercaptoacetate 
• 63547-24-0 modafinil acid 
• 63547-23-9 (diphenylmethyl)(ethyl acetate)sulfide 
• 63547-22-8 (benzhydrylthio)acetic acid 
• 91-01-0 1,1-Diphenylmethanol 
• 74-88-4 methyl iodide 
• 112111-45-2 (R)-Modafinil acid 
• 67-56-1 methanol 

Downstream Products

• 1726-02-9 bis(diphenylmethyl)disulfide 
• 112111-43-0 Nuvigil 

Relevant articles and documents

ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE

D The present invention relates to ion pair catalysts (I) comprising the cationic bisguanidinium ligand (A) and diperoxomolybdate anion (B). The present invention also relates to ion pair catalysts (III) comprising the cationic bisguanidinium ligand (C) and peroxotungstate anion (D). It further relates to the use of the said catalysts in the manufacture of enantiomerically enriched sulfoxides.

NOVEL CRYSTALLINE POLYMORPH OF ARMODAFINIL AND AN IMPROVED PROCESS FOR PREPARATION THEREOF

The present invention relates to a novel crystalline polymorph of armodafinil. In another aspect the invention relates to an improved process for preparation of the novel polymorph of armodafinil.

AN IMPROVED PROCESS FOR THE PREPARATION OF ARMODAFINIL

The invention encompasses processes for preparing intermediates, such as R-modafinic acid or (R)-C1-2 alkyl ester, of modafinic acid, and the conversion of the intermediates to armodafinil.