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Usage

Uses

Used in Polymer and Coating Production:
3-CHLORO-3'-METHYLBENZOPHENONE is used as a photoinitiator for the production of polymers and coatings. Its ability to absorb UV radiation allows it to initiate polymerization reactions, which are essential in creating durable and high-quality polymers and coatings.
Used in UV-Curable Inks and Adhesives:
In the manufacturing of UV-curable inks and adhesives, 3-CHLORO-3'-METHYLBENZOPHENONE serves as a crucial component. Its photoinitiating properties enable the rapid curing of inks and adhesives under UV light, ensuring fast and efficient production processes.
Used in Plastics Industry:
3-CHLORO-3'-METHYLBENZOPHENONE is utilized in the plastics industry as a component in the production of various types of plastics. Its role in initiating polymerization reactions contributes to the creation of plastics with specific properties, such as durability and flexibility.
Used in Dye Manufacturing:
In the dye manufacturing process, 3-CHLORO-3'-METHYLBENZOPHENONE is employed as a key component. Its ability to initiate polymerization reactions aids in the synthesis of dyes with desired characteristics, such as color intensity and stability.
Used in Pharmaceutical Production:
3-CHLORO-3'-METHYLBENZOPHENONE is also used in the pharmaceutical industry for the manufacturing of various drugs. Its photoinitiating properties can be harnessed in the synthesis of pharmaceutical compounds, contributing to the development of effective and innovative medications.

InChI:InChI=1/C14H11ClO/c1-10-4-2-5-11(8-10)14(16)12-6-3-7-13(15)9-12/h2-9H,1H3

Upstream product

• 134-62-3 N,N-Diethyl-3-methylbenzamide 
• 30070-63-4 meta-chlorobenzoic anhydride 
• 7294-50-0 tri-o-tolylboroxine 
• 21436-44-2 3-methylbenzoic acid anhydride 
• 7519-92-8 tris(3-chlorophenyl)boroxine 
• 201230-82-2 carbon monoxide 
• 456-39-3 3-chlorobenzenediazonium tetrafluoroborate 
• 937-01-9 trimethyl(3-methylphenyl)stannane 

Downstream Products

• 1267636-78-1 3-(3-chlorobenzoyl)benzaldehyde 

Relevant academic research and scientific papers

Redox-Neutral ortho Functionalization of Aryl Boroxines via Palladium/Norbornene Cooperative Catalysis

Palladium/norbornene (Pd/NBE) cooperative catalysis, also known as the Catellani reaction, has become an increasingly useful method for site-selective arene functionalization; however, certain constraints still exist because of its intrinsic mechanistic pathway. Herein, we report a redox-neutral ortho functionalization of aryl boroxines via Pd/NBE catalysis. An electrophile, such as carboxylic acid anhydrides or O-benzoyl hydroxylamines, is coupled at the boroxine ortho position, and a proton as the second electrophile is introduced at the ipso position. This reaction does not require extra oxidants or reductants and avoids stoichiometric bases or acids, thereby tolerating a wide range of functional groups. In particular, orthogonal chemoselectivity between aryl iodide and boroxine moieties is demonstrated, which could be used to control reaction sequences. Finally, a deuterium-labeling study supports the ipso protonation pathway. This unique mechanistic feature could inspire the development of a new class of Pd/NBE-catalyzed transformations.Poly-substituted aromatics are ubiquitously found in drugs and agrochemicals. To realize streamlined synthesis, it is highly attractive if functional groups can be site-selectively introduced at unactivated positions with common arene starting materials. Here, a method is developed to directly introduce acyl and amino groups at unactivated ortho positions of readily available aryl boron compounds. Compared with the known ortho functionalization approaches, this method does not require stoichiometric bases, external oxidants, or reductants. Consequently, the reaction is chemoselective: a wide range of functional groups, including highly reactive aryl iodides, can be tolerated. The primary innovation lies in the use of a proton to terminate the ipso aryl intermediate and regenerate the active palladium catalyst. This unique mode of reactivity in the palladium/norbornene catalysis should open the door for developing new redox-neutral methods for site-selective arene functionalization.A redox-neutral ortho functionalization of aryl boroxines via palladium/norbornene cooperative catalysis is developed. The ortho amination and acylation are achieved with carboxylic acid anhydrides and O-benzoyl hydroxylamines as an electrophile, respectively, whereas protonation occurs at the ipso position. This transformation avoids using either extra oxidants and reductants or stoichiometric bases and acids. In addition, orthogonal chemoselectivity between aryl iodide and boroxine moieties is demonstrated for pathway divergence.

The Halogen–Samarium Exchange Reaction: Synthetic Applications and Kinetics

Fast I/Sm and Br/Sm exchanges take place when various aromatic or heterocyclic iodides and bromides are treated with nBu2SmCl?4 LiCl and nBu3Sm?5 LiCl, respectively. The resulting organosamarium reagents were efficiently quenched with aldehydes, ketones, and imines. Also, they undergo acylations when treated with N,N-dimethylamides leading to ketones. The rate of the Br/Sm exchange for a typical aryl bromide was determined and found to be 8.5×105 faster than the Br/Mg exchange, indicating that the rate of a metal-exchange is related to the ionic character of the carbon–metal bond and to the metal electronegativity.

New synthesis of biaryls via Rh-catalyzed decarbonylative Suzuki-coupling of carboxylic anhydrides with arylboroxines

The catalytic cross-coupling of aromatic carboxylic anhydrides or acid chlorides with triarylboroxines has been achieved for the first time under decarbonylation, giving rise to the unsymmetrical biaryls rather than the expected diaryl ketones. This new decarbonylative Suzuki coupling, catalyzed by a [Rh(ethylene)2Cl]2/KF system, can be applied to aromatic, heteroaromatic and vinylic carboxylic anhydrides, potentially opening up new perspectives for the use of carboxylic acid derivatives as substrates in biaryl syntheses.

Reaction of Diazonium Salts with Transition Metals. Part 13. Palladium-catalyzed Carbonylative Coupling of Arenediazonium Salts with Organotin Reagents to give Aromatic Ketones

Palladium-catalyzed reactions of arenediazonium salts (ArN2X; Ar=Y-Ph, Y=H, 2-, 3-, 4-Me, 2-Ph, 2-, 3-MeO, 2-, 3-, 4-Cl, 4-Br, 4-I, 2-, 3-, and 4-NO2, X=BF4 and PF6) with carbon monoxide and organostannanes (R4Sn, R=Me, Et, and Ph; RSnMe3, R=Ph, 2-, 3-, 4-MeC6H4, and 4-ClC6H4; RSnEt3, R=4-NO2C6H4; RSnBu3, R=Ph) gave aromatic ketones (ArCOR) in good yields (40-95percent) at room temperature.

Benzophenones and benzhydrols

Compounds having the formula STR1 WHERE X is --CO-- or --CHOH--, Y and Z are halogen, alkyl, trifluoromethyl, alkoxy, hydroxy, nitro, cyano, carboxy, carbalkoxy, carbamoyl, or alkylthio, and m and n are 0, 1, or 2 Are useful in controlling undesirable secondary growth in plants, particularly sucker growth in tobacco.