71428-89-2

Usage

Uses

Used in Clinical Diagnostics:
Crotonyl glycine is utilized as a biomarker in clinical urine tests for the detection and monitoring of disorders of the mitochondrial fatty acid oxidation pathway. Its elevated levels in urine indicate the presence of such metabolic disorders, aiding in their diagnosis and management.
Used in Medical Research:
In the field of medical research, crotonyl glycine serves as a valuable tool for studying the mechanisms and impacts of mitochondrial fatty acid oxidation disorders. Understanding its role in these conditions can contribute to the development of targeted therapies and interventions.
Used in Pharmaceutical Development:
Crotonyl glycine may also be employed in the development of pharmaceuticals aimed at addressing or mitigating the effects of disorders related to mitochondrial fatty acid oxidation. Its unique biochemical properties could potentially be leveraged in the creation of novel therapeutic agents.
Used in Metabolic Pathway Analysis:
In the study of metabolic pathways, crotonyl glycine is used as an indicator to analyze and understand the processes involved in the metabolism of amino acids, particularly lysine, and the implications of their disruption in various metabolic disorders.

InChI:InChI=1/C6H9NO3/c1-2-3-5(8)7-4-6(9)10/h2-3H,4H2,1H3,(H,7,8)(H,9,10)

Upstream product

• 10487-71-5 crotonyl chloride 
• 56-40-6 glycine 
• 107-93-7 (E)-but-2-enoic acid 
• 625-35-4 trans-chrotonyl chloride 

Downstream Products

• 80589-24-8 4-ethoxymethylene-2-propenyl-4H-oxazol-5-one 
• 191223-09-3 (S)-2-[2-((E)-But-2-enoylamino)-acetylamino]-4-methyl-pentanoic acid 4-nitro-phenyl ester 
• 200940-00-7 (Z)-4-(4-hydroxybenzylidene)-1,2-dimethyl-1H-imidazol-5(4H)-one 
• 433218-99-6 3,5-dihydro-5-(4-hydroxybenzylidene)-3-methyl-2-propen-1-yl-4H-imidazol-4-one 
• 52507-17-2 (Z)-4-((2-methyl-5-oxooxazol-4(5H)-ylidene)methyl)phenyl acetate 
• 191223-03-7 ((E)-But-2-enoylamino)-acetic acid 4-nitro-phenyl ester 

Relevant academic research and scientific papers

PYRONE COMPOUND AND ITS USE FOR PEST CONTROL

A pyrone compound represented by formula (1) has an excellent controlling effect on pests. Since the compound of formula (1) has a controlling activity on pests, the compound is useful as an active ingredient of a pest control agent.

Synthesis and spectroscopic studies of model red fluorescent protein chromophores.

[reaction: see text]. Here we describe the synthesis and spectroscopic characterization of two compounds designed to model the chromophore in DsRed, a red fluorescent protein. Comparison with model green fluorescent protein (GFP) chromophores indicates th

N-crotonoyl derivatives of oligopeptides and their copolymers with N-vinylpyrrolidone

A series of N-crotonoyl derivatives of oligopeptides are prepared. The possibility of preparing their water-soluble copolymers with N-vinylpyrrolidone, characterized by narrow molecular-weight distribution, is examined.

N-Acylglycines: Gas chromatographic mass spectrometric identification and determination in urine by selected ion monitoring

Eleven biologically interesting N-acylglycines have been synthesized and the gas chromatographic and mass spectrometric properties of their trimethylsilyl derivatives studied. A sharp and reproducible gas chromatographic peak could be obtained for each n-acylglycine as the N,O-bis(trimethylsilyl)-N-acylglycine. By the use of these derivatives a sensitive and specific selected ion monitoring method for the determination of N-acylglycines in human urine has been developed.