71441-09-3

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid is used as a pharmaceutical compound for its potential therapeutic effects. Its unique molecular structure allows it to interact with specific biological targets, making it a candidate for the development of new drugs.
Used in Cosmetic Industry:
In the cosmetic industry, ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid may be used as an active ingredient in skincare products due to its potential benefits for skin health and appearance.
Used in Chemical Research:
ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid is also utilized in chemical research as a starting material or intermediate for the synthesis of other complex organic molecules, contributing to the advancement of chemical science and technology.
Used in Retinoid Applications:
Ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid is used as a retinoid in the treatment of various skin conditions. Its structural similarity to vitamin A allows it to inhibit human epidermal keratinocyte RNase P activity and tRNA biogenesis, potentially leading to improved skin health and appearance.

Safety Profile

An experimental teratogen. Otherexperimental reproductive effects. Mutation data reported.When heated to decomposition it emits acrid smoke andirritating fumes.

InChI:InChI=1/C26H32O2/c1-7-28-24(27)20-10-8-19(9-11-20)16-18(2)21-12-13-22-23(17-21)26(5,6)15-14-25(22,3)4/h8-13,16-17H,7,14-15H2,1-6H3/b18-16+

Upstream product

• 6683-46-1 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 6287-86-1 p-ethoxycarbonylbenzaldehyde 
• 75-36-5 acetyl chloride 
• 17610-21-8 1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth-2-yl)ethanone 
• 71441-08-2 ethyl 4-(diethoxyphosphorylmethyl)benzoate 
• 69251-24-7 [1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-ethyl]-triphenylphosphonium bromide 
• 64-17-5 ethanol 
• 141-52-6 sodium ethanolate 
• 69251-25-8 5,6,7,8-tetrahydro-α,5,5,8,8-pentamethyl-2-naphthalene methanol 
• 69251-26-9 2-(bromoethyl)-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene 

Downstream Products

• 71441-48-0 1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-[(E)-α-methyl-p-vinylstyryl]naphthalene 
• 71489-76-4 4-nitrobenzyl p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-benzoate 
• 71441-51-5 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]benzoic acid benzyl ester 
• 71441-39-9 p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-benzoic acid 2-diethylamino-ethyl ester 
• 71441-52-6 2-hydroxyethyl p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-benzoate 
• 71441-36-6 p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-benzoic acid diethylamide 
• 71441-50-4 (E)-p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-cinnamic acid ethyl ester 
• 71441-55-9 6-{(E)-2-[4-((E)-3-Methoxy-propenyl)-phenyl]-1-methyl-vinyl}-1,1,4,4-tetramethyl-1,2,3,4-tetrahydro-naphthalene 
• 71441-53-7 (E)-3-{4-[(E)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-phenyl}-prop-2-en-1-ol 
• 71441-29-7 p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-benzoic acid monoethylamide 
• 78315-04-5 (E)-4-<2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-methylethenyl>benzoyl chloride 
• 71441-38-8 p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-benzoic acid isopropyl ester 
• 71441-32-2 p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-benzyl methyl ether 
• 71441-40-2 p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-benzaldehyde 

Relevant academic research and scientific papers

A method for synthesizing substituted diphenyl derivatives

The invention relates to a synthesis method of a compound shown in Formula (I). A compound shown in Formula (III) is prepared via reaction of a compound shown in Formula (II) with a phase transfer catalyst, and the compound shown in Formula (I) is prepared via direct hydrolysis of the compound shown in Formula (III).

18-20 MEMBER BI-POLYCYCLIC COMPOUNDS

The invention relates to 18-20 member bi-polycyclic compounds, methods of making these compounds, and methods of using them in treating hyperproliferative disorders (e.g., cancer) and non-malignant tumors; promoting muscle formation; inhibiting muscle degeneration or the loss of muscle mass or muscle function; and myofibers ex vivo.

A-[(E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPTHALENYL)-1-PROPENYL]BENZOIC ACID ANALOGS AND METHOD OF MANUFACTURE AND AND USE THEREOF

Analogs of 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1 - propenyl]benzoic acid and methods of manufacture and use thereof, such as for use in cancer prevention and treatment.

Stilbene derivatives

This invention is directed to 5,6,7,8-tetrahydro-naphthyl or indanyl stilbene derivatives which are useful as tumor inhibiting agents, in the treatment of neoplasms, dermatological conditions and rheumatic illnesses.

Arotinoids, a new class of highly active retinoids

The synthesis and biological activity of new aromatic retinoids are reported. The most active ones belong to a chemical class of compounds, which we have termed 'arotinoids'. For the compound p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl)]-benzoic acid ethyl ester, a therapeutic potency in the antipapilloma test was found which exceeds that of retinoic acid by a factor of 8000, while the concurrently observed toxic hypervitaminosis A effects are only increased by a factor of 800. The structural relationship of the arotinoids with retinoic acid is demonstrated; the arotinoids contain the retinoic acid carbon skeleton in a fixed cisoid geometric conformation.