71500-03-3Relevant academic research and scientific papers
NOVEL FUNCTIONALIZED 5-(PHENOXYMETHYL)-1,3-DIOXANE ANALOGS EXHIBITNG CYTOCHROME P450 INHIBITION
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Paragraph 0196; 0197, (2015/04/15)
Pharmaceutical compositions described in this document comprise 5-(phenoxymethyl)-1,3-dioxane analogs having a disease-modifying action in the treatment of diseases associated with the production of cortisol that include metabolic syndrome, obesity, headache, depression, hypertension, diabetes mellitus, Cushing's Syndrome, pseudo-Cushing syndrome, cognitive impairment, dementia, heart failure, renal failure, psoriasis, glaucoma, cardiovascular disease, cancer, stroke, incidentalomas, or any diseases involving the overproduction of cortisol.
One-step conversion of acetophenones to α-haloacetophenone dimethyl acetals using DCDMH/DBDMH and molecular sieve in methanol
Zhou, Bin,Chen, Zizhan,Zheng, Zubiao,Han, Bingbing,Zou, Xinzhuo
experimental part, p. 1445 - 1453 (2012/04/17)
Using DCDMH/DBDMH as N-halo reagent, piperidine as catalyst, and 4-A molecular sieve as water-removing agent, α-haloacetophenone dimethyl acetals were directly obtained from the solvent of methanol. As to the substrates with electronwithdrawing groups, the conversions were 80-100%. Copyright Taylor & Francis Group, LLC.
A versatile rhodium catalyst for acetalization reactions under mild conditions
Ott,Ramos Tombo,Schmid,Venanzi,Wang,Ward
, p. 6151 - 6154 (2007/10/02)
Carbonyl compounds are readily acetalized under mild conditions in the presence of catalytic amounts of Rh(III)triphos moieties.
EXAMINATION OF BY-PRODUCTS FORMED UPON REACTING TRIALKYL PHOSPHITES WITH 2,4-DICHLOROPHENACYLIDENE BROMIDE AS A MECHANISTIC PROBE OF PERKOW REACTION
Koziara, Anna,Mloykowska, Barbara,Majewski, Piotr,Sledzinski, Bogdan,Zwierzak, Andrzej
, p. 399 - 409 (2007/10/02)
Besides the expected O,O-dialkyl-O--2-bromovinyl phosphates the formation of their structural analogs devoid of bromine or having two bromine atoms at the terminal position of vinyl group along with α-alkoxy-β-bromo-2,4-dichlorostyrene, α-alkoxy-β,β-dibromo-2,4-dichlorostyrene, and 2,4-dichlorophenacyl bromide was observed in Perkow reactions between trialkyl phosphites and chromatographically pure 2,4-dichlorophenacylidene bromide.The total quantity of side products markedly increases with increasing polarity of solvent.The formation of all the above mentioned compounds can be plausibly explained by assuming an intimate or solvent separated ion-pair as a common intermediate.
Antimicrobial and plant-growth-regulating triazole derivatives
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, (2008/06/13)
Novel 1-(β-aryl)ethyl-1H-1,2,4-triazole ketals useful for their antimicrobial and plant-growth regulating activities.
