7151-53-3

Upstream product

• 940-48-7 benzaldehyde acetylhydrazone 
• 100-52-7 benzaldehyde 
• 1068-57-1 acetic acid hydrazide 
• 14849-49-1 acetic acid benzylidene-hydrazide 
• 75-36-5 acetyl chloride 
• 555-96-4 Benzylhydrazine 
• 100-44-7 benzyl chloride 
• 41097-64-7 (E)-benzaldehyde hydrazone 
• 79-20-9 acetic acid methyl ester 

Downstream Products

• 64512-84-1 (2-Benzyl-1-acetyl-carbazinsaeure)-ethylester 
• 101435-28-3 4-Phenyl-2-benzyl-1-acetyl-semicarbazid 
• 95684-00-7 Acetic acid N'-benzyl-N'-(3-oxo-butyl)-hydrazide 
• 92521-89-6 1-acetyl-2-benzyl-5-hydroxypyrazolidine 
• 104637-69-6 Essigsaeure-<2-(methylaminosulfonyl)-2-(phenylmethyl)>hydrazid 
• 104637-70-9 Essigsaeure-<2-(aminosulfonyl)-2-(phenylmethyl)>hydrazid 
• 4046-03-1 2-methyl-5-phenyl-[1,3,4]oxadiazole 
• 940-48-7 benzaldehyde acetylhydrazone 
• 158838-06-3 Ethyl 2-<(3-Acetyl-2-benzylcarbazoyl)amino>acetate 
• 7696-79-9 1-Acetyl-2-(2-chlor-allyl)-2-benzyl-hydrazin 
• 25695-52-7 2-acetyl-1-benzyl-(3ar,9bc)-1,2,3,3a,4,9b-hexahydro-chromeno[4,3-c]pyrazole 
• 53370-82-4 N-Acetyl-α-azaphenyalanin-phenylester 

Relevant academic research and scientific papers

Metal-Free Synthesis of 1,3,4-Oxadiazoles from N′-(Arylmethyl)hydrazides or 1-(Arylmethyl)-2-(arylmethylene)hydrazines

An efficient and versatile metal-free synthesis of 1,3,4-oxadiazoles from N′-(arylmethyl)hydrazides or 1-(arylmethyl)-2-(arylmethylene)hydrazines through oxidative dehydrogenation is reported. A range of 2,5-disubstituted 1,3,4-oxadiazoles were prepared by treating N′-(arylmethyl)hydrazides with (diacetoxyiodo)benzene in acetonitrile or by treating 1-(arylmethyl)-2-(arylmethylene)hydrazines with [bis(trifluoroacetoxy)iodo]benzene in methyl tert-butyl ether. Aldehyde N-acylhydrazones and aldazines were initially generated in situ as intermediates.

Synthesis and biological activity of P2-P4 azapeptidomimetic P1-argininal and P1-ketoargininamide derivatives: A novel class of serine protease inhibitors

Molecular modeling and topographic considerations of the thrombin-specific sequences Boc-Asp-Pro-Arg-TS or Ac-d-Phe-Pro-Arg-TS (TS = transition state analog electrophilic center) and related scaffolds led to the design of novel P2-P4-azapeptidomimetic P1-argininal and P1-ketoargininamide derivatives (3a-j). The synthesis and biological activity of these potential serine protease inhibitors are presented.

1,3-Dipolar cycloreversion of a 1,3,4-oxadiazolidine as a controlled azomethine imine surrogate for pyrazolidine synthesis

Azomethine imines were generated in a controlled manner through a thermally allowed 1,3-dipolar cycloreversion of 1,3,4-oxadiazolidines and subsequently trapped with dipolarophiles. This method results in the construction of the pyrazolidine heterocycles. A new method for the selective formation of the key semicarbazide substrate, from benzylidene hydrazone, is also disclosed.

1-Acyl-2-alkylhydrazines by the Reduction of Acylhydrazones

1-Acyl-2-alkylhydrazines were easily prepared by the reduction of acylhydrazones with triethylsilane in the presence of trifluoroacetic acid.