716-41-6

Basic information

• Product Name: 2-Methanesulfonylamino-benzoic acid methyl ester
• Synonyms: 2-Methanesulfonylamino-benzoic acid methyl ester;methyl 2-methanesulfonamidobenzoate;methyl 2-(methylsulfonamido)benzoate
• CAS NO: 716-41-6
• Molecular Formula: C₉H₁₁NO₄S
• Molecular Weight: 229.25294
• Mol File: 716-41-6.mol
• Article Data: 20

Chemical Properties

• Melting Point: 89-90 °C
• Boiling Point: 361.7±44.0 °C(Predicted)
• Appearance: /
• Density: 1.366±0.06 g/cm3(Predicted)
• PKA: 7.70±0.10(Predicted)
• CAS DataBase Reference: 2-Methanesulfonylamino-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methanesulfonylamino-benzoic acid methyl ester(716-41-6)
• EPA Substance Registry System: 2-Methanesulfonylamino-benzoic acid methyl ester(716-41-6)

Safety Data

• Hazardous Substances Data: 716-41-6(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 134-20-3 2-carbomethoxyaniline 

Downstream Products

• 152342-43-3 2-(N-Mesyl-2-methoxycarbonylanilino)-8-methoxy-1,4-naphthoquinone 
• 152342-38-6 2-(N-Mesyl-2-methoxycarbonylanilino)-5,6-dimethoxy-1,4-benzoquinone 
• 152342-36-4 2-(N-Mesyl-2-methoxycarbonylanilino)-5-methoxy-1,4-benzoquinone 
• 152342-37-5 2-(N-Mesyl-2-methoxycarbonylanilino)-6-methoxy-1,4-benzoquinone 
• 152342-44-4 2-(N-Mesyl-2-methoxycarbonylanilino)-5-methoxy-1,4-naphthoquinone 
• 36881-76-2 methyl 2-(N-methyl-N-(methanesulfonyl)amino)benzoate 

Relevant articles and documents

Synthesis, X-ray crystal and monoamine oxidase inhibitory activity of 4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine 5,5-dioxides: In vitro studies and docking analysis

We report the synthesis and biological evaluation of two new series of 2-amino-6-benzyl-4-phenyl-4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine-3?carbonitrile 5,5-dioxides and 2-amino-6-methyl-4-phenyl-4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine-3?carbon

4 - hydroxy - 3 - benzoyl - 1 - alkyl - 2, 1 - benzothiazine - 2, 2 - dioxide derivative and application thereof

The invention relates to a 4-hydroxy-3-benzoyl-1-alkyl-2, 1-benzothiazine-2, 2-dioxide derivative and application. The structure general formula of the compound is (I), and R1 and R2 are defined according to the claim. 2-methyl anthranilate is used as raw

Discovery of (2-benzoylethen-1-ol)-containing 1,2-benzothiazine derivatives as novel 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibiting-based herbicide lead compounds

A series of (2-benzoylethen-1-ol)-containing benzothiazine derivatives was synthesized, and their herbicidal activities were first evaluated. The bioassay results indicated that some of 3-benzoyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-1,1-dioxide derivatives displayed good herbicidal activity in greenhouse testing, especially, compound 4w had good pre-emergent herbicidal activities against Brassica campestris, Amaranthus retroflexus and Echinochloa crusgalli even at a dosage of 187.5 g ha-1. More importantly, compound 4w displayed significant inhibitory activity against Arabidopsis thaliana HPPD and was identified as the most potent candidate with IC50 value of 0.48 μM, which is better than the commercial herbicide sulctrione (IC50 = 0.53 μM) and comparable with the commercial herbicide mesotrione (IC50 = 0.25 μM). The structure-activity relationships was studied and provided some useful information for improving herbicidal activity. The present work indicated that (2-benzoylethen-1-ol)-containing 1,2-benzothiazine motif could be a potential lead structure for further development of novel HPPD inhibiting-based herbicides.