36881-76-2

Basic information

• Product Name: ASISCHEM W27133
• Synonyms: ASISCHEM W27133;METHYL 2-(METHYL(METHYLSULFONYL)AMINO)BENZOATE;2-(mesyl-methyl-amino)benzoic acid methyl ester;2-(methyl-methylsulfonylamino)benzoic acid methyl ester;MLS000063338;SDCCGMLS-0013536.P002;SMR000075018;ST012303
• CAS NO: 36881-76-2
• Molecular Formula: C₁₀H₁₃NO₄S
• Molecular Weight: 243.28
• Mol File: 36881-76-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ASISCHEM W27133(CAS DataBase Reference)
• NIST Chemistry Reference: ASISCHEM W27133(36881-76-2)
• EPA Substance Registry System: ASISCHEM W27133(36881-76-2)

Safety Data

• Hazardous Substances Data: 36881-76-2(Hazardous Substances Data)

Upstream product

• 74-87-3 methylene chloride 
• 716-41-6 methyl N-mesylanthranilate 
• 134-20-3 2-carbomethoxyaniline 
• 74-88-4 methyl iodide 

Downstream Products

• 36881-68-2 1-methyl-2,2,4-trioxo-1,2,3,4-tetrahydro-2λ⁶-benzo[c][1,2]thiazine-3-carboxylic acid anilide 
• 36881-73-9 1-methyl-2,2,4-trioxo-1,2,3,4-tetrahydro-2λ⁶-benzo[c][1,2]thiazine-3-carboxylic acid 4-methyl-anilide 
• 36881-70-6 1-methyl-2,2,4-trioxo-1,2,3,4-tetrahydro-2λ⁶-benzo[c][1,2]thiazine-3-carboxylic acid 4-bromo-anilide 
• 36881-71-7 1-methyl-2,2,4-trioxo-1,2,3,4-tetrahydro-2λ⁶-benzo[c][1,2]thiazine-3-carboxylic acid 3-chloro-anilide 
• 36881-69-3 4-hydroxy-1-methyl-2,2-dioxo-1,2-dihydro-2λ⁶-benzo[c][1,2]thiazin-3-carboxylic acid 4-methoxyphenylamide 
• 36881-74-0 1-methyl-2,2,4-trioxo-1,2,3,4-tetrahydro-2λ⁶-benzo[c][1,2]thiazine-3-carboxylic acid 2-methoxy-anilide 
• 36881-72-8 1-methyl-2,2,4-trioxo-1,2,3,4-tetrahydro-2λ⁶-benzo[c][1,2]thiazine-3-carboxylic acid 4-nitro-anilide 
• 1088979-71-8 N-(2-(hydroxymethyl)phenyl)-N-methylmethanesulfonamide 

Relevant articles and documents

Synthesis, X-ray crystal and monoamine oxidase inhibitory activity of 4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine 5,5-dioxides: In vitro studies and docking analysis

We report the synthesis and biological evaluation of two new series of 2-amino-6-benzyl-4-phenyl-4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine-3?carbonitrile 5,5-dioxides and 2-amino-6-methyl-4-phenyl-4,6-dihydrobenzo[c]pyrano[2,3-e][1,2]thiazine-3?carbon

4 - hydroxy - 3 - acyl - 1 - alkyl - 2, 1 - benzothiazine - 2, 2 - dioxide derivative and application thereof

The invention relates to a 4-hydroxy-3-acyl-1-alkyl-2,1-benzothiazine-2,2-dioxide ramification and application thereof. The 4-hydroxy-3-acyl-1-alkane-2,1-benzothiazine-2,2-dioxide derivative is obtained through sulfoamidation, alkylation, ring closure and

COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS

The present application provides novel optionally substituted fused pyridine and pyrimidine bicyclic compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful in co-regulating FAK and/or Src activity by administering a therapeutically effective amount of one or more of the compounds to a subject. By doing so, these compounds are effective in treating conditions associated with the dysregulation of the FAK and/or Src pathway. Advantageously, these compounds perform as dual FAK and/or Src inhibitors. A variety of conditions can be treated using these compounds and include diseases which are characterized by inflammation or abnormal cellular proliferation. In one embodiment, the disease is cancer.