71648-27-6Relevant academic research and scientific papers
A fast and practical synthesis of tert-butyl esters from 2-tert-butoxypyridine using boron trifluoride·diethyl etherate under mild conditions
La, Minh Thanh,Kim, Hee-Kwon
, p. 3748 - 3754 (2018/05/28)
A practical direct preparation of tert-butyl esters from 2-tert-butoxypyridine has been developed. This system features the use of boron trifluoride·diethyl etherate in toluene solvent to rapidly achieve the reaction at room temperature. Using this reaction protocol, a variety of tert-butyl esters were synthesized from several different carboxylic acids at high yields. This practical procedure provides a promising and effective approach to the protection of carboxylic acids with a tert-butyl group.
Asymmetric p(O) - π(Triazine) conjugation in the formally symmetric bis(4,6-dimethoxy-1,2,5-triazinyl) ether in its crystal structure
Glowka,Blaszczyk,Olczak,Kaminska,Kamiuski
experimental part, p. 2163 - 2172 (2010/09/03)
Reported is the crystal structure of a formally symmetric bis(s-triazinyl) ether obtained as a by-product in the acylation reaction of less reactive nucleophiles with 2-acyloxy-4,6-dimethoxy-1,3,5-triazines. The title ether shows conformational asymmetry evidenced by different orientations of the four methoxy groups and the two aromatic rings in relation to the central etheric plane. Differentiation of the two O-C(triazine) bond lengths of the bis(triazinyl) ether can be correlated with the angles between s-triazine rings with the central etheric plane, indicating different degree of conjugation of the two π-systems with a lone pair of the central oxygen atom. It seems that primary reason for the observed asymmetry is crystal packing, causing different orientations of methoxy groups, which in turn induced bond lengths alternation in the j-triazine rings affecting their conjugations with central O atom through AGIBA effect. The experimental observations are in agreement with ab initio calculation.
2-Acyloxy-4,6-dimethoxy-1,3,5-triazine - A new reagent for ester synthesis
Kaminska, Janina E.,Kaminski, Zbigniew J.,Gora, Jozef
, p. 593 - 596 (2007/10/03)
2-Acyloxy-4,6-dimethoxy-1,3,5-triazines obtained in reaction between carboxylic acid and 2-chloro-4,6-dimethoxy-1,3,5-triazine were used as acylating agents for the synthesis of esters from primary, secondary, and tertiary alcohols. Because of mild acylation conditions the method could be applied to esterification of labile alcohols with aromatic and aliphatic (also α-branched) acids in good yields.
