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2-[1-(4-METHOXYPHENYL)ETHYLIDENE]-1-HYDRAZINECARBOXAMIDE, also known as N′-(4-methoxybenzylidene)hydrazide, is a hydrazinecarboxamide derivative with the molecular formula C11H14N4O2. It is a chemical compound that features an aromatic phenyl ring with a methoxy substituent and an ethylidene group attached to the hydrazinecarboxamide core. This versatile compound is commonly used in organic synthesis and pharmaceutical research, and has been studied for its potential applications in drug development and as a building block for the synthesis of other organic compounds.

717-14-6

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717-14-6 Usage

Uses

Used in Pharmaceutical Research:
2-[1-(4-METHOXYPHENYL)ETHYLIDENE]-1-HYDRAZINECARBOXAMIDE is used as a research compound for its potential applications in drug development. Its unique structure and functional groups make it a promising candidate for the design and synthesis of new pharmaceutical agents.
Used in Organic Synthesis:
In the field of organic synthesis, 2-[1-(4-METHOXYPHENYL)ETHYLIDENE]-1-HYDRAZINECARBOXAMIDE serves as a building block for the synthesis of other organic compounds. Its reactivity and structural features allow it to be incorporated into various chemical reactions, leading to the formation of diverse organic molecules with potential applications in various industries.
Used in Chemical Research:
2-[1-(4-METHOXYPHENYL)ETHYLIDENE]-1-HYDRAZINECARBOXAMIDE is also utilized in chemical research to study its properties and reactivity. Understanding its behavior in different chemical environments can provide valuable insights into the development of new synthetic methods and the discovery of novel compounds with specific functionalities.
Used in Chemical Industry:
In the chemical industry, 2-[1-(4-METHOXYPHENYL)ETHYLIDENE]-1-HYDRAZINECARBOXAMIDE may be employed as an intermediate in the production of various chemical products. Its versatility and reactivity make it a valuable component in the synthesis of a wide range of compounds used in different applications, such as dyes, pigments, and other specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 717-14-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,1 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 717-14:
(5*7)+(4*1)+(3*7)+(2*1)+(1*4)=66
66 % 10 = 6
So 717-14-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H13N3O2/c1-7(12-13-10(11)14)8-3-5-9(15-2)6-4-8/h3-6H,1-2H3,(H3,11,13,14)/b12-7+

717-14-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[1-(4-Methoxyphenyl)ethylidene]-1-hydrazinecarboxamide

1.2 Other means of identification

Product number -
Other names 1-(4-methoxy-phenyl)-ethanone semicarbazone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:717-14-6 SDS

717-14-6Relevant articles and documents

Synthesis and evaluation of antimicrobial and anticancer activities of 3-phenyl-1-phenylsulfonyl pyrazoles containing an aminoguanidine moiety

Huang, Yushan,Hu, Hongmei,Yan, Rui,Lin, Liwen,Song, Mingxia,Yao, Xiaodong

, (2020/10/15)

A series of 3-phenyl-1-phenylsulfonyl pyrazoles containing an aminoguanidine moiety was designed, synthesized, and evaluated for their antimicrobial and anticancer activities. The majority of the target compounds showed broad-spectrum antimicrobial activi

Synthesis and biological evaluation of some pyrazole derivatives, containing (Thio) semicarbazide, as dual anti-inflammatory antimicrobial agents

Liang, Zhaochang,Huang, Yuping,Wang, Shiben,Deng, Xianqing

, p. 1020 - 1030 (2019/10/28)

Background: Several series of pyrazole derivatives containing (thio) semicarbazide (4a-4h, 5a-5l, 6a-6f, 7a-7c) were designed and synthesized to screen dual inflammatory and antimicrobial activities. Methods: The products were characterized by1

Synthesis and antitubercular and antibacterial activity of some active fluorine containing quinoline–pyrazole hybrid derivatives

Nayak, Nagabhushana,Ramprasad, Jurupula,Dalimba, Udayakumar

, p. 59 - 68 (2017/11/28)

In an attempt to develop newer antitubercular and antibacterial agents against the increasing bacterial resistance, we have designed new quinoline–pyrazole analogs (8a–u) following the molecular hybridization approach. The structure of one of the final compounds, 8a was unambiguously confirmed by single crystal X-ray diffraction (SC-XRD) analysis. The target compounds were evaluated for their antitubercular activity against Mycobacterium tuberculosis and antibacterial activity against three common pathogenic bacterial strains. Four derivatives (8b, 8c, 8j and 8o) displayed significant antitubercular activity. The compounds derived from 8-trifluoromethylquinoline and 6-fluoroquinoline scaffolds with halogen substitution on the pyrazole ring exhibited superior inhibition activity than corresponding 6-methoxyquinoline analogs. The cytotoxic studies revealed that the active compounds are nontoxic to normal Vero cell lines with selectivity index values ≥10, which indicate the suitability of these compounds for further drug development. The in silico molecular docking study demonstrated strong binding affinity of the compounds with the target enzymes (InhA, CYP121 and TMPK) of M. tuberculosis. Further, the in vitro antibacterial activity of compounds 8b, 8c, 8d and 8g is comparable with that of the reference drug, Ciprofloxacin.

Preparation of 2-Arylethynylselanylacetonitriles from 4-Aryl-1,2,3-selenadiazoles

O'Connor,Sachinvala,Ganjian

, p. 1167 - 1169 (2015/08/06)

Base decomposition of 4-(substituted phenyl)-1,2,3-selenadiazoles at room temperature resulted in 2-(substituted phenyl)-ethynylselenolate anions, which were immediately reacted with bromoacetonitrile to give a series of 2-(substituted phenyl)ethynylselan

Structure-activity relationship study of a novel necroptosis inhibitor, necrostatin-7

Zheng, Weihong,Degterev, Alexei,Hsu, Emily,Yuan, Junying,Yuan, Chengye

scheme or table, p. 4932 - 4935 (2009/05/26)

Necroptosis is a regulated caspase-independent cell death mechanism characterized by morphological features resembling non-regulated necrosis. Necrotatin-7 (Nec-7), a novel potent small-molecule inhibitor of necroptosis, is structurally distinct from previously described necrostatins (Nec-1, Nec-3, Nec-4 and Nec-5). Here, we describe a series of structural modifications and the structure-activity relationship (SAR) of the Nec-7 series for inhibiting necroptosis.

Synthesis of 3-substituted arylpyrazole-4-carboxylic acids

Lebedev,Lebedeva,Sheludyakov,Kovaleva,Ustinova,Kozhevnikov

, p. 782 - 789 (2007/10/03)

A method was suggested for preparing previously unknown 3-aryl-substituted pyrazole-4-carboxylic acids, involving Vilsmeier formylation of semicarbazones of 26 available mono- and disubstituted acetophenones and 2-acetylthiophene followed by oxidation of

Some aryl semicarbazones possessing anticonvulsant activities

Dimmock, J. R.,Sidhu, K. K.,Tumber, S. D.,Basran, S. K.,Chen, M.,et al.

, p. 287 - 302 (2007/10/02)

A number of aryl semicarbazones displayed anticonvulsant activity in the maximal electroshock (MES) and subcutaneous pentylenetetrazone (scPTZ) screens when administered intraperitoneally to mice.When given by the oral route to rats, protections was affor

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