71797-10-9Relevant academic research and scientific papers
A new method for the deprotection of benzyl ethers or the selective protection of alcohols
Madsen, Jacob,Viuf, Christel,Bols, Mikael
, p. 1140 - 1146 (2007/10/03)
A new selective method for the deprotection of benzyl ethers situated next to alcohols in the α, β, or γ position is presented which uses either NIS or DIB/I2 as a reagent. After initial formation of a hypoiodite intermediate, the reaction is b
A new intramolecular reaction for the regioselective debenzylation or protection of alcohols
Madsen, Jacob,Bols, Mikael
, p. 3177 - 3178 (2007/10/03)
Strained benzylidene acetals such as 1 can be prepared with a new intramolecular reaction that allows the selective removal of benzyl protecting groups neighboring free OH groups, without attacking other benzyl groups. The mechanism of this reaction, which is useful for carbohydrate synthesis, probably proceeds via ionic intermediates with neighboring group participation.
Crossed Aldol Reactions of Dioxolans
Cambie, Richard C.,Rutledge, Peter S.,Watson, Paul A.,Woodgate, Paul D.
, p. 1939 - 1949 (2007/10/02)
The crossed aldol reactions of some cyclohexyl and cyclohexenyl dioxolans with the silyl enol ether of cyclohexanone have, in general, been shown to result in directed opening of the acetal.However, only limited stereoselectivity results at the termini of the new carbon-carbon bond.
