71945-53-4

Basic information

• Product Name: benzyl [1,1’-biphenyl]-4-carboxylate
• Synonyms: benzyl [1,1’-biphenyl]-4-carboxylate
• CAS NO: 71945-53-4
• Molecular Weight: 288.346
• Mol File: 71945-53-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: benzyl [1,1’-biphenyl]-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl [1,1’-biphenyl]-4-carboxylate(71945-53-4)
• EPA Substance Registry System: benzyl [1,1’-biphenyl]-4-carboxylate(71945-53-4)

Safety Data

• Hazardous Substances Data: 71945-53-4(Hazardous Substances Data)

Upstream product

• 92-66-0 4-bromo-1,1'-biphenyl 
• 104-57-4 benzyl formate 
• 14002-51-8 4-biphenyl-carboxylic acid chloride 
• 100-51-6 benzyl alcohol 
• 136618-42-3 4-iodobenzoic acid benzyl ester 
• 71-43-2 benzene 
• 3218-36-8 4-Phenylbenzaldehyde 
• 108-88-3 toluene 
• 92-92-2 biphenyl-4-carboxylic acid 
• 5896-17-3 2-(phenylmethoxy)benzaldehyde 
• 5447-87-0 2-(1-phenylethylidene)propanedinitrile 
• 1212022-43-9 benzyl 2-(acetoxymethyl)buta-2,3-dienoate 
• 121699-36-3 benzyltriethylammonium nitrite 
• 6976-20-1 1-([1,1′-biphenyl]-4-yl)-2-methylpropan-1-one 

Relevant articles and documents

Organocatalytic synthesis of (Het)biaryl scaffoldsviaphotoinduced intra/intermolecular C(sp2)-H arylation by 2-pyridone derivatives

A uniqueN,O-bidentate ligand 6-oxo-1,6-dihydro-pyridone-2-carboxylic acid dimethylamide (L1) catalyzed direct C(sp2)-H (intra/intermolecular) arylation of unactivated arenes has been developed to expedite access to (Het)biaryl scaffolds under UV-irradiation at room temperature. The protocol tolerated diverse functional groups and substitution patterns, affording the target products in moderate to excellent yields. Mechanistic investigations were also carried out to better understand the reaction pathway. Furthermore, the synthetic applicability of this unified approach has been showcasedviathe construction of biologically relevant 4-quinolone, tricyclic lactam and sultam derivatives.

Palladium-Catalyzed Carbonylative Synthesis of Benzyl Benzoates Employing Benzyl Formates as Both CO Surrogates and Benzyl Alcohol Sources

An efficient and convenient palladium-catalyzed carbonylation reaction for the synthesis of benzyl benzoates from aryl bromides has been developed. Benzyl formates have been explored as a new type of efficient and useful CO sources and also reaction partners. A wide range of benzyl benzoates was obtained in good to excellent yields.

N-Methylpyrrolidin-2-one-Promoted Formation of Functional Esters through C–O Bond Cleavage

Trifluoromethanesulfonic acid catalyzed C–O bond cleavage leading to the preparation of functional esters in the presence of N-methylpyrrolidin-2-one (NMP) was accomplished. Various substrates were well tolerated, and a gram-scale experiment was successfully realized. DFT calculations indicated that NMP plays a decisive role in accelerating nucleophilic attack of the functional acid to generate the functional esters in chlorobenzene.