136618-42-3

Basic information

• Product Name: Benzyl4-iodobenzoate
• Synonyms: Benzyl4-iodobenzoate
• CAS NO: 136618-42-3
• Molecular Formula: C₁₄H₁₁IO₂
• Molecular Weight: 338
• Mol File: 136618-42-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 397.6±25.0 °C(Predicted)
• Appearance: /
• Density: 1.609±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Benzyl4-iodobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl4-iodobenzoate(136618-42-3)
• EPA Substance Registry System: Benzyl4-iodobenzoate(136618-42-3)

Safety Data

• Hazardous Substances Data: 136618-42-3(Hazardous Substances Data)

Usage

General Description

Benzyl 4-iodobenzoate is a chemical compound that belongs to the class of benzyl esters. It is composed of a benzyl group attached to a 4-iodobenzoate group, making it a benzyl ester derivative of 4-iodobenzoic acid. Benzyl4-iodobenzoate is commonly used in organic synthesis as a reagent for various chemical reactions, including esterifications and coupling reactions. Its unique structure and reactivity make it valuable for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it is utilized in the production of fragrances and flavorings due to its aromatic properties. Overall, benzyl 4-iodobenzoate is an important chemical compound with wide-ranging applications in the field of organic chemistry.

Upstream product

• 619-58-9 4-iodobenzoic acid 
• 100-51-6 benzyl alcohol 
• 22426-93-3 N-(benzyloxy)-4-iodobenzamide 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 619-44-3 methyl 4-iodobenzoate 
• 7285-83-8 2,4,6-tris(benzyloxy)-1,3,5-triazine 
• 15164-44-0 p-(iodophenyl)carboxaldehyde 
• 100-39-0 benzyl bromide 
• 62-23-7 4-nitro-benzoic acid 
• 122-04-3 4-nitro-benzoyl chloride 
• 14786-27-7 benzyl 4-nitrobenzoate 
• 19008-43-6 benzyl 4-aminobenzoate 
• 1711-02-0 4-iodobenzoic acid chloride 

Downstream Products

• 189393-75-7 4-((diethoxyphosphoryl)difluoromethyl)benzoic acid 

Relevant articles and documents

ZWITTERIONIC CATALYSTS FOR (TRANS)ESTERIFICATION: APPLICATION IN FLUOROINDOLE-DERIVATIVES AND BIODIESEL SYNTHESIS

An amide/iminium zwitterion catalyst has a catalyst pocket size that promotes transesterification and dehydrative esterification. The amide/iminium zwitterions are easily prepared by reacting aziridines with aminopyridines. The reaction can be applied a wide variety of esterification processes including the large-scale synthesis of biodiesel. The amide/iminium zwitterions allow the avoidance of strongly basic or acidic condition and avoidance of metal contamination in the products. Reactions are carried out at ambient or only modestly elevated temperatures. The amide/iminium zwitterion catalyst is easily recycled and reactions proceed in high to quantitative yields.

Amide/Iminium Zwitterionic Catalysts for (Trans)esterification: Application in Biodiesel Synthesis

A class of zwitterionic organocatalysts based on an amide anion/iminium cation charge pair has been developed. The zwitterions are easily prepared by reacting aziridines with aminopyridines. They are catalytically applicable to transesterifications and dehydrative esterifications. Mechanistic studies reveal that the amide anion and iminium cation work synergistically in activating the reaction partners, with the iminium cationic moiety interacting with the carbonyl substrates through nonclassical hydrogen bonding. The reaction can be applied to large-scale synthesis of biodiesel under mild conditions.

Organocatalyzed anodic oxidation of aldehydes

A method for the catalytic formation of electroauxiliaries and subsequent anodic oxidation has been developed. The process interfaces N-heterocyclic carbene-based organocatalysis with electro-organic synthesis to achieve direct oxidation of catalytically generated electroactive intermediates. We demonstrate the applicability of this method as a one-pot conversion of aldehydes to esters for a broad range of aldehyde and alcohol substrates. Furthermore, the anodic oxidation reactions are very clean, producing only H2 gas as a result of cathodic reduction.