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  • High purity 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride CAS No.:720720-96-7

    Cas No: 720720-96-7

  • USD $ 2.0-2.0 / Kilogram

  • 1 Kilogram

  • 10 Metric Ton/Month

  • Hangzhou Think Chemical Co. Ltd
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  • High Quality 99% 720720-96-7 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Manufacturer

    Cas No: 720720-96-7

  • USD $ 0.1-0.1 / Gram

  • 1 Gram

  • 100 Metric Ton/Year

  • Xi'an Xszo Chem Co., Ltd.
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720720-96-7 Usage


5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique structure, which includes a thiazolo[5,4-c]pyridine core with a methyl group and a carboxylic acid functionality. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is soluble in water and is commonly used in the pharmaceutical industry for the development of novel therapeutic agents.


Used in Pharmaceutical Industry:
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives. These derivatives are known for their antithrombotic properties, making them valuable in the development of medications to prevent blood clot formation and related disorders.
Additionally, 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is used as a reagent in the synthesis of diamide derivatives. These compounds have been identified as potent factor Xa (FXa) inhibitors, which play a crucial role in the coagulation cascade. FXa inhibitors are an important class of anticoagulant drugs that help prevent the formation of blood clots, reducing the risk of stroke, deep vein thrombosis, and other thrombotic events.
Furthermore, 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride serves as an intermediate for the production of Edoxaban (E555520), a direct oral anticoagulant drug. Edoxaban is used to treat and prevent various thrombotic conditions, such as atrial fibrillation, deep vein thrombosis, and pulmonary embolism. Its development relies on the unique properties of the intermediate compound, which contributes to its efficacy and safety profile.

Check Digit Verification of cas no

The CAS Registry Mumber 720720-96-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,0,7,2 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 720720-96:
137 % 10 = 7
So 720720-96-7 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name 5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid,hydrochloride

1.2 Other means of identification

Product number -
Other names QC-12

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:720720-96-7 SDS

720720-96-7Relevant articles and documents

Method for preparing edoxaban from trichloroacetophenone onium salt derivatives


Paragraph 0068-0073, (2020/07/21)

The invention provides a method for preparing edoxaban by using 2, 2, 2-trichloro-1-(4, 5, 6, 7-tetrahydro-5-methylthiazolo[5, 4-c]pyridinium-1-yl) ethanone chloride. The preparation method comprisesthe following steps: preparing 2, 2, 2-trichloro-1-(4, 5, 6, 7-tetrahydro-5-methylthiazolo[5, 4-c]pyridinium-1-yl) ethanone chloride, namely 109C5-11; the invention discloses a preparation method of N1[(1S, 2R, 4S)-2-amino-4-[(dimethylamino) carbonyl]cyclohexyl]-N2(5-chloro-2-pyridyl) oxalamide dimesylate, namely 109T2-31. The 109C5-11 is used as an acylation reagent to prepare the edoxaban with 109T2-31. The preparation method comprises the following steps: preparing the edoxaban by using the 109C5-11 as the acylation reagent; the novel method overcomes the defect that expensive condensing agents EDCI.HCl and activating agents HOBt need to be used in the prior art. The new method provided by the invention is beneficial to more economically and more efficiently realizing industrial scale production of the Edoxaban p-toluenesulfonate hydrate.



Paragraph 0160; 0161; 0162; 0163; 0164; 0165; 0166-0172, (2017/03/21)

An object of the present invention is to provide a novel method for producing a compound, a salt thereof, or a hydrate of the compound or the salt, which is an FXa inhibitor. The object can be attained by a production method in which a production method via a compound represented by formula (1-1), etc., from a compound represented by the following formula (1-x), etc., is used for a method for producing a compound represented by the following formula (X), etc. [wherein X represents a halogen atom or the like, and R1 represents an optionally substituted phenyl group].



Page/Page column 53, (2008/06/13)

The present invention provides processes for producing a compound (5) based on the following reaction scheme. [F1]

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