7208-42-6

Basic information

• Product Name: Ribitol pentaacetate
• Synonyms: Ribitol pentaacetate
• CAS NO: 7208-42-6
• Molecular Formula: C₁₅H₂₂O₁₀
• Molecular Weight: 0
• Mol File: 7208-42-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ribitol pentaacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ribitol pentaacetate(7208-42-6)
• EPA Substance Registry System: Ribitol pentaacetate(7208-42-6)

Safety Data

• Hazardous Substances Data: 7208-42-6(Hazardous Substances Data)

Upstream product

• 5328-37-0 L-arabinose 
• 108-24-7 acetic anhydride 
• 488-82-4 D-Arabitol 
• 137734-28-2 Acetic acid (1R,2R,3R)-1-acetoxymethyl-2,3,4-trihydroxy-butyl ester 
• 100-39-0 benzyl bromide 
• 127-08-2 potassium acetate 
• 64-19-7 acetic acid 
• 6018-27-5 1,2,3,4,5-pentapentanol 
• 488-81-3 Adonitol 
• 137734-28-2 Acetic acid (1S,2R,3R)-1-acetoxymethyl-2,3,4-trihydroxy-butyl ester 
• 18524-23-7 DL-erythro-pentene-⁽¹⁾-triol-(3.4.5)-triacetate 
• 7732-18-5 water 
• 87-99-0 XYLITOL 
• 609-06-3 L-xylose 

Downstream Products

• 87-99-0 XYLITOL 

Relevant articles and documents

A novel low-molecular-mass pumpkin polysaccharide: Structural characterization, antioxidant activity, and hypoglycemic potential

The novel natural low-molecular-mass polysaccharide (SLWPP-3) from pumpkin (Cucurbia moschata) was separated from the waste supernatant after macromolecular polysaccharide production and purified using a DEAE cellulose-52 column and gel-filtration chromatography. Chemical and instrumental studies revealed that SLWPP-3 with a molecular mass of 3.5 kDa was composed of rhamnose, glucose, arabinose, galactose and uronic acid with a weight ratio of 1: 1: 4: 6: 15, and primarily contained →3,6)-β-D-Galp-(1→, →4)-α-GalpA-(1→(OMe), →4)-α-GalpA-(1→, →2,4)-α-D-Rhap-(1→, →3)-β-D-Galp-(1→, →4)-α-D-Glcp, and →4)-β-D-Galp residues in the backbone. The branch chain passes were connected to the main chain through the O-4 atom of glucose and O-3 atom of arabinose. Physiologically, the ability of SLWPP-3 to inhibit carbohydrate-digesting enzymes and DPPH and ABTS radicals, as well as protect pancreatic β cells from oxidative damage by decreasing MDA levels and increasing SOD activities, was confirmed. The findings elucidated the structural types of pumpkin polysaccharides and revealed a potential adjuvant natural product with hypoglycemic effects.

Method for preparing amino alcohol derivative

The invention provides a method for preparing an amino alcohol derivative. The method is characterized in that substitution reaction is carried out on ester groups of dihydric alcohol carboxylic esteror polyhydric alcohol carboxylic ester to obtain the amino alcohol derivative, wherein the amidogen is derived into sulfonamido, and at least one carboxylic ester group remains. The method for preparing the amino alcohol derivative has the advantages that the raw materials are cheap and obtained easily, the use quantity of catalysts is low, the reaction condition is simple, and the selectivity ofproducts is high.

Chemical synthesis method of L-xylose

The invention discloses a novel chemical synthesis method of L-xylose. According to the novel chemical synthesis method, 2, 2-dimethoxypropane protects hydroxyl of L-(-)2,3-dihydroxypropionaldehyde, and then a product is coupled with (1-bromovinyl)trimethylsilane so as to establish a basic framework of a target product; after production of 99% of ee is guaranteed by a sharpless epoxidation or Jacobsen-Katsuki expoxidation method, a three-membered ring is opened by protecting groups to guarantee that the configuration thereof is unchanged; then, the hydroxyl group produced by selectively removing one protecting group is oxidized into an aldehyde group; finally, the remaining protecting groups are removed to obtain the target product L-xylose, and the total yield is 46-48%. By the novel chemical synthesis method, the condition is mild, raw materials are cheap and easy to obtain, and a synthesis thought and the synthesis method are provided for chemical synthesis of a series of aldoses.

Discovery and characterization of family 39 glycoside hydrolases from rumen anaerobic fungi with polyspecific activity on rare arabinosyl substrates

Enzyme activities that improve digestion of recalcitrant plant cell wall polysaccharides may offer solutions for sustainable industries. To this end, anaerobic fungi in the rumen have been identified as a promising source of novel carbohydrate active enzymes (CAZymes) that modify plant cell wall polysaccharides and other complex glycans. Many CAZymes share insufficient sequence identity to characterized proteins from other microbial ecosystems to infer their function; thus presenting challenges to their identification. In this study, four rumen fungal genes (nf2152, nf2215, nf2523, and pr2455) were identified that encode family 39 glycoside hydrolases (GH39s), and have conserved structural features with GH51s. Two recombinant proteins, NF2152 and NF2523, were characterized using a variety of biochemical and structural techniques, and were determined to have distinct catalytic activities. NF2152 releases a single product, β1,2-arabinobiose (Ara2) from sugar beet arabinan (SBA), and β1,2-Ara2 and α-1,2-galactoarabinose (Gal-Ara) from rye arabinoxylan (RAX). NF2523 exclusively releases α-1,2-Gal-Ara from RAX, which represents the first description of a galacto-(-1,2)-arabinosidase. Both β-1,2-Ara2 and α-1,2-Gal-Ara are disaccharides not previously described within SBA and RAX. In this regard, the enzymes studied here may represent valuable new biocatalytic tools for investigating the structures of rare arabinosyl-containing glycans, and potentially for facilitating their modification in industrial applications.

Isolation, purification and structural characterization of a water-soluble polysaccharide HM41 from Halenia elliptica D. Don

A water-soluble polysaccharide, HM41, was obtained from Halenia elliptica D. Don by acidic ethanol fractionation and gel filtration. Its homogeneity was confirmed by chromatography using multiple systems. HM41 was composed of rhamnose (Rha), arabinose (Ara), xylose (Xyl), mannose (Man), galactose (Gal), glucose (Glc) with a molar ratio of 1.0:5.5:1.8:3.0:9.4:21. The average molecular weight of HM41 was approximately 1.17 × 104. Periodate oxidation, Smith degradation, methylation and GC, IR, NMR, XRD, GC-MS analysis were used for the structural analysis of HM41. Its main chain was composed mainly of β-(1 → 4)Gal, β-(1 → 4)Glc and β-(1 → 6)Glc. β-(1 → 4)Gal were substituted at 6-O and on average there were 14 branches among 23 main chain residues; (1 → 4)Glc had no branch; (1 → 6)Glc were substituted at 3-O and on average there were 9 branches among 14 main chain residues. The side chain was composed of (1 → 3,6)-Rha, (1 → 4)/(1 → 5)-Ara, (1 → 4)/(1 → 5)-Xyl, (1 → 4,6)-Man and (1 → 2)-Glc. The terminal residue was composed of Ara, Xyl, Man, Gal, and Glc. Then, we demonstrated that HM and HM41 had strong scavenging activities in vitro hydroxyl. Overall, HM and HM41 may have potential applications in the antioxidants for medical and food industry.

I2/ionic liquid as a highly efficient catalyst for per-O-acetylation of sugar under microwave irradiation

A practical and highly efficient approach was developed to synthesize peracetylated sugar derivatives using a recyclable iodine/PEG400-based ionic liquid catalyst (I2/IL). The peracetylated sugars were readily obtained in a few minutes in excellent yields (90%-99%, 13 examples) on a multi-gram scale (50.0 mmol) by the reaction of sugar and acetic anhydride under microwave irradiation in the absence of a volatile organic solvent. The desired product was easily obtained by simple extraction with toluene from the reaction mixture, and I2/ILs can be readily recovered and reused at least six times without obvious loss in the yield. When the scale of the per-O-acetylation reaction was increased to 50.0 mmol, the desired product was still obtained in 90% yield after five recycles.

Characterization of the chemical diversity of glycosylated mycosporine-like amino acids in the terrestrial cyanobacterium Nostoc commune

Mycosporine-like amino acids (MAAs) are UV-absorbing pigments, and structurally unique glycosylated MAAs are found in the terrestrial cyanobacterium Nostoc commune. In this study, we examined two genotypes of N. commune colonies with different water extract UV-absorption spectra. We found structurally distinct MAAs in each genotype. The water extract from genotype A showed a UV-absorbing spectrum with an absorption maximum at 335 nm. The extract contained the following compounds: 7-O-(β-arabinopyranosyl)-porphyra-334 (478 Da), pentose-bound shinorine (464 Da), hexose-bound porphyra-334 (508 Da) and porphyra-334 (346 Da). The water extract from genotype B showed a characteristic UV-absorbing spectrum with double absorption maxima at 312 and 340 nm. The extract contained hybrid MAAs (1050 Da and 880 Da) with two distinct chromophores of 3-aminocyclohexen-1-one and 1,3-diaminocyclohexen linked to 2-O-(β-xylopyranosyl)-β-galactopyranoside. A novel 273-Da MAA with an absorption maximum at 310 nm was also identified in genotype B. The MAA consisted of a 3-aminocyclohexen-1-one linked to a γ-aminobutyric acid chain. These MAAs had potent radical scavenging activities in vitro and the results confirmed that the MAAs have multiple roles as a UV protectant and an antioxidant relevant to anhydrobiosis in N. commune. The two genotypes of N. commune exclusively produced their own characteristic glycosylated MAAs, which supports that MAA composition could be a chemotaxonomic marker for the classification of N. commune.

Isolation and characterization of a hyperbranched proteoglycan from Ganoderma Lucidum for anti-diabetes

Presently, an efficient protein tyrosine phosphatase 1B (PTP1B) inhibitor, named FYGL-n, was isolatedfrom Ganoderma Lucidum and characterized for its structure and bioactivity. Structure and chain con-formation of FYGL-n based on both chemical and spectroscopic analysis showed that FYGL-n was ahyperbranched heteropolysaccharide bonded with protein via both serine and threonine residues by O-type glycoside, and showed a sphere observed by AFM. Specifically, monosaccharide compositionindicated that FYGL-n consisted of D-arabinose, D-galactose, L-rhamnose and D-glucose in a mole ratio of 0.08:0.21:0.24:0.47, with a molecular mass of 72.9 kDa. The analysis of amino acids in FYGL-n indicatedthat there were 16 common amino acids, among which aspartic acid, glycine, serine, alanine, glutamicacid and threonine were the dominant components. Also it was demonstrated that FYGL-n could inhibitthe PTP1B activity on a competitive mechanism in vitro.

Silica-supported boric acid catalyzed synthesis of dihydropyrimidin-2-ones, bis(indolyl)methanes, esters and amides

Silica-supported boric acid (H3BO3-SiO2) has been established as a green, efficient and recyclable catalyst for the synthesis of dihydropyrimidin-2-ones, bis(indolyl)methanes, and acetylation of alcohols, phenols, amines and thiols under solvent free conditions. The main features of the present method include clean reaction, mild conditions, low loading of environment friendly catalyst and easy workup procedure. The catalyst can be recycled at least five times without any significant loss in activity.

New 9,19-cycloartenol glycosides isolated from the roots of Cimicifuga simplex and their anti-inflammatory effects

Two new cycloartenol triterpene saponins, 3β,16α-dihydroxy-12-acetoxy-16,22-cyclo-23-ketone-24R,25-epoxy-cycloartane-3-O-β-d-galactopyranoside (1), 3β,16α-dihydroxy-12-acetoxy-16,22-cyclo-23-ketone-24R,25-epoxy-cycloartane-7-ene-3-O-β-d-xylopyranoside (2), were isolated from the ethyl acetate soluble fraction of the roots of Cimicifuga simplex Wormsk. Their structures were established by detailed spectroscopic analysis, including extensive 2D NMR data. Their anti-proinflammatory activities were also carried out by LPS-stimulated IL-6, IL-23 and TNF-α genes expression in RAW cells in vitro using Q-PCR method.