722492-05-9Relevant academic research and scientific papers
New highly active taxoids from 9β-dihydrobaccatin-9,10-acetals. Part 5
Takeda, Yasuyuki,Uoto, Kouichi,Iwahana, Michio,Jimbo, Takeshi,Nagata, Motoko,Atsumi, Ryo,Ono, Chiho,Tanaka, Noriko,Terasawa, Hirofumi,Soga, Tsunehiko
, p. 3209 - 3215 (2007/10/03)
To improve the metabolic stability of 3, which exhibited both in vitro antitumor activity and in vivo efficacy by both iv and po administration, we designed and synthesized new taxane analogues. Most of the synthetic compounds maintained excellent antitum
