2150-41-6

Basic information

• Product Name: METHYL 2,4-DIMETHOXYBENZOATE
• Synonyms: METHYL 2,4-DIMETHOXYBENZOATE;2,4-Dimethoxybenzoic acid methyl ester;Methyl 2,4-dimethoxybenzoate 98%;RARECHEM AL BF 0025
• CAS NO: 2150-41-6
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Product Categories: C10 to C11;Carbonyl Compounds;Esters
• Mol File: 2150-41-6.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 294-296 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.194 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000921mmHg at 25°C
• Refractive Index: n20/D 1.548(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 2,4-DIMETHOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2,4-DIMETHOXYBENZOATE(2150-41-6)
• EPA Substance Registry System: METHYL 2,4-DIMETHOXYBENZOATE(2150-41-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 2150-41-6(Hazardous Substances Data)

Usage

Description

METHYL 2,4-DIMETHOXYBENZOATE is an organic compound with the chemical formula C10H12O4. It is characterized by its high antifeedant index, making it a promising candidate for practical applications in various fields.

Uses

Used in Chemical Synthesis:
METHYL 2,4-DIMETHOXYBENZOATE is used as a key intermediate in the synthesis of 1,5-diaryl-1,3,5-pentanetriones, which are important compounds in the field of organic chemistry.
Used in Agriculture:
METHYL 2,4-DIMETHOXYBENZOATE is used as an antifeedant in agriculture for protecting planted seedlings in the field. Its high antifeedant index makes it an effective candidate for deterring pests and ensuring the healthy growth of crops.

InChI:InChI=1/C10H12O4/c1-12-7-4-5-8(10(11)14-3)9(6-7)13-2/h4-6H,1-3H3

Upstream product

• 186581-53-3 diazomethane 
• 124-38-9 carbon dioxide 
• 51241-41-9 m-methoxyphenyl i-propyl ether 
• 79128-08-8 1,3-diisopropoxybenzene 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 151-10-0 1,3-Dimethoxybenzene 
• 108-46-3 recorcinol 
• 616-38-6 carbonic acid dimethyl ester 
• 5446-02-6 4-methoxymethylsalicylate 
• 3186-53-6 O-methyl S-p-methylphenyl thiocarbonate 
• 133730-34-4 2,4-dimethoxyphenylboronic acid 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 7438-18-8 2,4-dimethoxybenzenediazonium tetrafluoroborate 

Downstream Products

• 94312-76-2 2,3-bis-(2,4-dimethoxy-phenyl)-3-oxo-propionitrile 
• 76832-37-6 2,4,2’,4’,2”,4”-hexamethoxytriphenylcarbinol 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 101442-26-6 3-(2,4-dimethoxy-phenyl)-3-oxo-2-phenyl-propionitrile 
• 273211-51-1 1-(2,4-dimethoxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propane-1,3-dione 
• 198351-03-0 8-Allyl-2-(2,4-dimethoxy-phenyl)-chromen-4-one 
• 103956-10-1 2,4-dimethoxybenzohydrazide 
• 174261-85-9 methyl 5-acetyl-2,4-dimethoxybenzoate 
• 5446-02-6 4-methoxymethylsalicylate 
• 1609699-52-6 methyl 5-((2-(5-bromopyridin-2-yl)hydrazono)methyl)-2,4-dimethoxybenzoate 
• 1609699-53-7 methyl 5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxybenzoate 
• 1609699-87-7 5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxybenzoic acid 
• 1609699-88-8 (5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxyphenyl)(4-methylpiperazin-1-yl)methanone 
• 1609699-89-9 (5-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dimethoxyphenyl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone 

Relevant articles and documents

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Synthesis, Antiproliferative and Antioxidant Activity of 3-Mercapto-1,2,4-Triazole Derivatives as Combretastatin A-4 Analogues

Two series of 3-mercapto-1,2,4-triazole derivatives containing alkoxy substituents different in size and position were synthesized and their structures were characterized by FT-IR, 1H NMR, 13C NMR spectroscopy and elemental analysis. The synthesized compounds were assessed for their antiproliferative activity against colon cancer cell line (SW480). The results indicated that the size and position of the alkoxy group significantly influenced the antiproliferative activity. The highest cancer cell growth inhibition values were observed for the compounds containing 3,4,5-trimethoxyphenyl groups in their structures (57.74, 54.14 and 60.70% at 50 μM for compounds 5a, 12b and 14, respectively). The synthesized compounds were also subjected to DPPH protocol for evaluating the antioxidant activity. The results showed that all compounds had moderate to high levels of antioxidant capacity as compared to ascorbic acid as standard, the highest free radical scavenging capacity of 75% was observed for compound 4a at 50 μM.

Synthesis of acyclic and cyclic phosphonates based on substituted 2-hydroxybenzylic alcohols

A convenient synthesis of benzylic phosphonates and 2,3-dihydrobenzo[d][1,2]oxaphosphole 2-oxides substituted at the aromatic ring, as well as their precursors, 2-hydroxybenzylic alcohols, from the derivatives of salicylic aldehyde, salicylic acid, and 2-hydroxyacetophenone bearing an additional hydroxy or methoxy group at the para position of the aromatic ring was developed. For the first time, the possibility of selective demethylation of the methoxy group positioned ortho to the methylene phosphonate fragment with retention of the methoxy group at the para position was shown.

Methylation of Aliphatic and Aromatic Carboxylic Acids with Dimethyl Carbonate under the Influence of Manganese and Iron Carbonyls

The synthesis of methyl esters has been carried out via the reaction of aliphatic and aromatic carboxylic acids with dimethyl carbonate in the presence of manganese and iron carbonyls. The optimal ratio of catalyst and reagents and other conditions for the synthesis of methyl esters of carboxylic acids with high yield have been found.