72402-71-2

Basic information

• Product Name: 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside
• CAS NO: 72402-71-2
• Molecular Formula: C₃₆H₃₁F₃N₂O₁₄
• Molecular Weight: 772.6315
• Mol File: 72402-71-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 920.9°C at 760 mmHg
• Flash Point: 510.7°C
• Density: 1.61g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.656
• CAS DataBase Reference: 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside(72402-71-2)
• EPA Substance Registry System: 3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-4-O-(4-nitrobenzoyl)-3-[(trifluoroacetyl)amino]hexopyranoside(72402-71-2)

Safety Data

• Hazardous Substances Data: 72402-71-2(Hazardous Substances Data)

Upstream product

• 21794-55-8 (+)-Daunomycinone 
• 73891-04-0 2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-(trifluoroacetamido)-L-arabino-hex-1-enitol 
• 14218-08-7 2,3,4-tri-O-benzoyl-α-L-rhamnopyranosyl bromide 
• 73864-38-7 2,3,6-tridesoxy-3-(trifluoroacetamido)-L-arabino-hex-1-enitol 
• 73864-37-6 3-amino-1,5-anhydro-2,3,6-tridesoxy-L-arabino-hex-1-enitol 
• 122-04-3 4-nitro-benzoyl chloride 
• 34820-21-8 1,5-anhydro-3,4-di-O-benzoyl-2,6-didesoxy-L-arabino-hex-1-enitol 
• 76739-66-7 3,4-di-O-acetyl-D-rhamnal 
• 73864-37-6 3-amino-1,5-anhydro-2,3,6-tridesoxy-D-ribo-hex-1-enitol 
• 72384-25-9 1,5-anhydro-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-D-ribo-hex-1-enitol 

Relevant articles and documents

SUBSTITUTIONS D'ESTERS ALLYLIQUES: PREPARATION DE GLYCALS AMINES EN C-3 ET ETUDE DE LEUR GLYCOSIDATION ACIDO-CATALYSEE. APPLICATION A L'HEMISYNTHESE DE GLYCOSIDES DU GROUPE DES ANTHRACYCLINES

3-Amino-1,5-anhydro-2,3,6-trideoxy-L-arabino- and -L-ribo-hex-1-enitol were prepared by substitution of the allylic ester function of 1,5-anhydro-3,4-di-O-benzoyl-2,6-dideoxy-L-arabino-hex-1-enitol with sodium azide, followed by reduction with lithium aluminium hydride.Glycosidation was performed with various alcohols, in particular daunomycinone.In the latter case, the partial synthesis of 4'-epi- and 3',4'-epi-daunorubicines was accomplished in three major steps.