7249-16-3Relevant articles and documents
Preparation process of dihydrooat alkaloid D
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Paragraph 0045-0052; 0065-0069, (2021/06/13)
The invention relates to a preparation process of dihydrooat alkaloid D. The preparation process comprises the following three steps: phenolic hydroxyl group protection, acylating chlorination and amidation, and hydrolysis deprotection, wherein p-hydroxyp
Ligand-Controlled Regioselective Hydrocarboxylation of Styrenes with CO2 by Combining Visible Light and Nickel Catalysis
Meng, Qing-Yuan,Wang, Shun,Huff, Gregory S.,Konig, Burkhard
supporting information, p. 3198 - 3201 (2018/03/13)
The ligand-controlled Markovnikov and anti-Markovnikov hydrocarboxylation of styrenes with atmospheric pressure of CO2 at room temperature using dual visible-light-nickel catalysis has been developed. In the presence of neocuproine as ligand, the Markovnikov product is obtained exclusively, while employing 1,4-bis(diphenylphosphino)butane (dppb) as the ligand favors the formation of the anti-Markovnikov product. A range of functional groups and electron-poor, -neutral, as well as electron-rich styrene derivatives are tolerated by the reaction, providing the desired products in moderate to good yields. Preliminary mechanistic investigations indicate the generation of a nickel hydride (H-NiII) intermediate, which subsequently adds irreversibly to styrenes.
Synthesis of a novel diarylheptanoid isolated from Zingiber officinale
Parker, Gregory D.,Seden, Peter T.,Willis, Christine L.
scheme or table, p. 3686 - 3689 (2009/10/04)
Syntheses of 4-acetoxy-2,6-disubstituted tetrahydropyrans via Prins cyclisation of homoallylic alcohols with benzylic aldehydes are described and the methodology is applied in the total synthesis of diarylheptanoid 1 confirming both the structure and abso
