7250-53-5

Basic information

• Product Name: Quinoline-5-carboxylic acid
• Synonyms: AKOS BBS-00005337;QUINOLINE-5-CARBOXYLIC ACID;RARECHEM AL BE 1510;5-quinolinecarboxylic acid ;Quinoline-5-carboxylic;Quinoline-5-carboxylicacid,98+%;NSC30045;Quinoline-5-carboxylic acid, 97+%
• CAS NO: 7250-53-5
• Molecular Formula: C₁₀H₇NO₂
• Molecular Weight: 173.17
• EINECS: -0
• Product Categories: Acids and Derivatives;Heterocycles;Quinoline Derivertives;quinoline
• Mol File: 7250-53-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: >300°C
• Boiling Point: 386.5 °C at 760 mmHg
• Flash Point: 187.5 °C
• Appearance: /
• Density: 1.339 g/cm³
• Vapor Pressure: 1.15E-06mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 0.97±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• BRN: 129178
• CAS DataBase Reference: Quinoline-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline-5-carboxylic acid(7250-53-5)
• EPA Substance Registry System: Quinoline-5-carboxylic acid(7250-53-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-36/38-22
• Safety Statements: 26-36-37/39-37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 7250-53-5(Hazardous Substances Data)

Usage

Uses

Quinoline-5-carboxylic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

InChI:InChI=1/C10H7NO2/c12-10(13)8-3-1-5-9-7(8)4-2-6-11-9/h1-6H,(H,12,13)/p-1

Upstream product

• 7661-55-4 5-methylquinoline 
• 99-05-8 meta-aminobenzoic acid 
• 56-81-5 glycerol 
• 5434-20-8 3-aminophthalic acid 
• 16675-62-0 methyl quinoline-5-carboxylate 
• 151-50-8 potassium cyanide 

Downstream Products

• 16675-62-0 methyl quinoline-5-carboxylate 
• 98421-25-1 quinoline-5-carboxylic acid ethyl ester 
• 118990-93-5 N-(2-Phenylethyl)-quinoline-6-carboxamide 
• 114527-54-7 1,2,3,4-tetrahydro-5-quinolinecarboxylic acid 
• 899431-51-7 N-benzylquinoline-5-carboxamide 
• 1344046-12-3 3-bromoquinoline-5-carboxylic acid 
• 939758-74-4 5-(trifluoromethyl)-1,2,3,4-tetrahydroquinoline 
• 342-30-3 5-(trifluoromethyl)quinolone 
• 1257524-04-1 5-{5-[2-(4-chloro-phenoxymethyl)-phenyl]-[1,3,4]oxadiazol-2-yl}-quinoline 
• 1257524-03-0 C₂₅H₁₉N₃O₂ 
• 1029491-93-7 C₁₈H₈Cl₃N₅S 
• 858784-68-6 N-(quinoline-5-carbonyl)-N'-(toluene-4-sulfonyl)-hydrazine 
• 96541-83-2 quinoline-5-carbohydrazide 
• 118128-78-2 ethyl ester of 1,2,3,4-tetrahydroquinoline-5-carboxylic acid 

Relevant articles and documents

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CYCLIC AMIDE DERIVATIVES AS INHIBITORS OF 11 - BETA - HYDROXYSTEROID DEHYDROGENASE AND USES THEREOF

The present invention relates to certain amide derivatives that have the ability to inhibit 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and which are therefore useful in the treatment of certain disorders that can be prevented or treated by inhibition of this enzyme. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of conditions such as non-insulin dependent type 2 diabetes mellitus (NIDDM), insulin resistance, obesity, impaired fasting glucose, impaired glucose tolerance, lipid disorders such as dyslipidemia, hypertension and as well as other diseases and conditions.

HIV protease inhibitors

HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.