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4-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)aniline is a complex organic chemical compound with the molecular formula C16H16N2O2S. It is a derivative of aniline, featuring a sulfonyl group attached to the 4-position of the aniline ring, which is further connected to a 3,4-dihydroisoquinolin-2(1H)-yl moiety. 4-(3,4-DIHYDROISOQUINOLIN-2(1H)-YLSULFONYL)ANILINE is known for its potential applications in the synthesis of pharmaceuticals and other organic compounds, particularly those involving the isoquinoline scaffold. Its structure provides a versatile platform for further chemical modifications, making it a valuable intermediate in the development of new drugs and other chemical products.

7252-02-0

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7252-02-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7252-02-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7252-02:
(6*7)+(5*2)+(4*5)+(3*2)+(2*0)+(1*2)=80
80 % 10 = 0
So 7252-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H16N2O2S/c16-14-5-7-15(8-6-14)20(18,19)17-10-9-12-3-1-2-4-13(12)11-17/h1-8H,9-11,16H2

7252-02-0Relevant academic research and scientific papers

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

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Paragraph 00576, (2018/08/03)

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors

Pingaew, Ratchanok,Prachayasittikul, Veda,Mandi, Prasit,Nantasenamat, Chanin,Prachayasittikul, Supaluk,Ruchirawat, Somsak,Prachayasittikul, Virapong

, p. 3472 - 3480 (2015/08/03)

Abstract A series of 1,4-disubstituted-1,2,3-triazoles (13-35) containing sulfonamide moiety were synthesized and evaluated for their aromatase inhibitory effects. Most triazoles with open-chain sulfonamide showed significant aromatase inhibitory activity

Novel 1,4-naphthoquinone-based sulfonamides: Synthesis, QSAR, anticancer and antimalarial studies

Pingaew, Ratchanok,Prachayasittikul, Veda,Worachartcheewan, Apilak,Nantasenamat, Chanin,Prachayasittikul, Supaluk,Ruchirawat, Somsak,Prachayasittikul, Virapong

, p. 446 - 459 (2015/10/05)

A novel series of 1,4-naphthoquinones (33-44) tethered by open and closed chain sulfonamide moieties were designed, synthesized and evaluated for their cytotoxic and antimalarial activities. All quinone-sulfonamide derivatives displayed a broad spectrum o

Design, synthesis and molecular docking studies of novel N-benzenesulfonyl-1,2,3,4-tetrahydroisoquinoline-based triazoles with potential anticancer activity

Pingaew, Ratchanok,Mandi, Prasit,Nantasenamat, Chanin,Prachayasittikul, Supaluk,Ruchirawat, Somsak,Prachayasittikul, Virapong

, p. 192 - 203 (2014/06/09)

A novel series of N-benzenesulfonyl-1,2,3,4-tetrahydroisoquinolines (14-33) containing triazole moiety were designed and synthesized through rational cycloadditions using the modified Pictet-Spengler reaction and the Click chemistry. Antiproliferative act

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