72524-20-0

Basic information

• Product Name: ethyl (E)-2,2-dimethyl-5-phenylpent-4-enoate
• Synonyms: ethyl (E)-2,2-dimethyl-5-phenylpent-4-enoate
• CAS NO: 72524-20-0
• Molecular Weight: 232.323
• Mol File: 72524-20-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl (E)-2,2-dimethyl-5-phenylpent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (E)-2,2-dimethyl-5-phenylpent-4-enoate(72524-20-0)
• EPA Substance Registry System: ethyl (E)-2,2-dimethyl-5-phenylpent-4-enoate(72524-20-0)

Safety Data

• Hazardous Substances Data: 72524-20-0(Hazardous Substances Data)

Upstream product

• 21040-45-9 Cinnamyl acetate 
• 31469-16-6 1-ethoxy-1-((trimethylsilyl)oxy)-2-methylpropene 
• 64-17-5 ethanol 
• 97-62-1 Ethyl isobutyrate 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 22768-07-6 (E)-ethyl 5-phenylpent-4-enoate 
• 7217-71-2 1-phenyl-2-propenyl acetate 
• 109756-13-0 E-ethyl 2-methyl-5-phenylpent-4-enoate 
• 74-88-4 methyl iodide 
• 4392-24-9 Cinnamyl bromide 

Downstream Products

• 260352-12-3 (E)-5-(4-chlorophenyl)-2,2-diphenylpent-4-enal 
• 72524-18-6 trans-2,2-dimethyl-5-phenyl-pent-4-enoic acid 
• 75107-76-5 5,5-Dimethyl-2-phenylcyclopent-2-enone 

Relevant articles and documents

Novel η3-allylpalladium-pyridinylpyrazole complex: Synthesis, reactivity, and catalytic activity for cyclopropanation of ketene silyl acetal with allylic acetates

Novel cationic η3-allylpalladium-pyridinylpyrazole complexes 1a and 1b were synthesized from 3-alkyl-5-(2-pyridinyl)pyrazole and η3-allylpalladium chloride dimer in the presence of AgBF4. Cationic complexes 1a and 1b were converted into neutral complexes 2a and 2b under basic conditions. These complexes were characterized by 1H, 13C, and 15N NMR studies. Neutral complexes 2a and 2b have high catalytic activity for cyclopropanation of ketene silyl acetals with allylic acetates. Comparison of the cationic and neutral complexes and the reaction mechanism of cyclopropanation were discussed.

Iminoxyl radical-promoted dichotomous cyclizations: Efficient oxyoximation and aminooximation of alkenes

A novel iminoxyl radical-involved metal-free approach to vicinal oxyoximation and aminooximation of unactivated alkenes is developed. This method utilizes the dichotomous reactivity of the iminoxyl radical to furnish a general difunctionalization on alkenes using simple tert-butyl nitrite (TBN) as the iminoxyl radical initiator as well the carbon radical trap. By using this protocol, oxime featured 4,5-dihydroisoxazoles and cyclic nitrones were facilely prepared from β,γ- and γ,δ-unsaturated ketoximes, respectively.

Asymmetric cyclopropanation of ketene silyl acetal with allylic acetate catalyzed by a palladium complex

The first asymmetric cyclopropanation of ketene silyl acetal with allylic acetate was achieved. New chiral oxazolidinylpyrazole ligands and their η3-allylpalladium complexes were synthesized. Reaction of cinnamyl acetate with ketene silyl acetal of ethyl isobutylate in the presence of a palladium complex gave a phenyl cyclopropane derivative in 20~ 54%ee.