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AIDS-125459, also known as 4-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)-N-(4-fluorophenyl)benzamide, is a potent and selective non-nucleoside reverse transcriptase inhibitor (NNRTI) that has been developed as a potential antiretroviral drug for the treatment of HIV-1 infection. It exhibits high binding affinity to the reverse transcriptase enzyme, thereby inhibiting the replication of the virus. The compound has demonstrated promising antiviral activity in preclinical studies, with a unique binding mode that differentiates it from other NNRTIs, potentially offering a new therapeutic option for patients with drug-resistant HIV strains.

7254-13-9

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7254-13-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7254-13-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7254-13:
(6*7)+(5*2)+(4*5)+(3*4)+(2*1)+(1*3)=89
89 % 10 = 9
So 7254-13-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H9N3O3S2/c1-7(15)13-11-12-6-10(19-11)18-9-4-2-8(3-5-9)14(16)17/h2-6H,1H3,(H,12,13,15)

7254-13-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[5-(4-nitrophenyl)sulfanyl-1,3-thiazol-2-yl]acetamide

1.2 Other means of identification

Product number -
Other names N-[5-(4-Nitro-phenylmercapto)-thiazol-2-yl]-acetamid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7254-13-9 SDS

7254-13-9Relevant academic research and scientific papers

Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same

-

, (2008/06/13)

Compounds of the formula: STR1 wherein A is S, SO, or SO2, R1 is H or acyl, R2 is H, alkyl, hydroxyalkyl, halogen or carboxy, and R3 is pyridyl are claimed. The compounds are useful as therapeutic agents for the treatment of e.g. rheumatism, nephritis and

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