7336-54-1

Basic information

• Product Name: 2-ACETAMIDO-5-BROMOTHIAZOLE
• Synonyms: 2-ACETAMIDO-5-BROMOTHIAZOLE;2-ACETYLAMINO-5-BROMOTHIAZOLE;AKOS BB-9164;N-(5-BROMO-THIAZOL-2-YL)-ACETAMIDE;2-Acetamido-5-bromo-1,3-thiazole;Acetamide, N-(5-bromo-2-thiazolyl)-
• CAS NO: 7336-54-1
• Molecular Formula: C₅H₅BrN₂OS
• Molecular Weight: 221.07
• Product Categories: Sulphur Derivatives
• Mol File: 7336-54-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.82 g/cm³
• Refractive Index: 1.657
• CAS DataBase Reference: 2-ACETAMIDO-5-BROMOTHIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETAMIDO-5-BROMOTHIAZOLE(7336-54-1)
• EPA Substance Registry System: 2-ACETAMIDO-5-BROMOTHIAZOLE(7336-54-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 7336-54-1(Hazardous Substances Data)

Usage

General Description

2-Acetamido-5-bromothiazole is a chemical compound with the molecular formula C6H6BrN3OS. It is a synthetic intermediate used in the production of pharmaceuticals and organic compounds. 2-ACETAMIDO-5-BROMOTHIAZOLE has a thiazole ring with a bromine atom and an acetamido group attached to it. It is commonly used in the synthesis of various drugs, agrochemicals, and materials for research purposes. 2-Acetamido-5-bromothiazole is also utilized in the development of bioactive molecules and pharmaceutical ingredients due to its unique structure and reactivity. However, it is important to handle this compound with care and follow proper safety protocols due to its potential hazards.

InChI:InChI=1/C5H5BrN2OS/c1-3(9)8-5-7-2-4(6)10-5/h2H,1H3,(H,7,8,9)

Upstream product

• 3034-22-8 5-bromo-2-aminothiazole 
• 108-24-7 acetic anhydride 
• 61296-22-8 5-bromothiazol-2-amine hydrobromide 
• 41731-33-3 2-bromo-4-aminothiazole 
• 2719-23-5 2-acetamidothiazole 

Downstream Products

• 59278-80-7 5-phenylsulfanyl-thiazol-2-ylamine 
• 533886-11-2 N-(5-p-tolylmercapto-thiazol-2-yl)-acetamide 
• 859462-91-2 N-[5-(4-chloro-phenylsulfanyl)-thiazol-2-yl]-acetamide 
• 7254-13-9 N-[5-(4-nitro-phenylsulfanyl)-thiazol-2-yl]-acetamide 
• 3034-22-8 5-bromo-2-aminothiazole 
• 140-40-9 Nitazole 
• 944804-63-1 (S)-N-(5-bromothiazol-2-yl)-N-(2-(1,3-dioxoisoindolin-2-yl)-3-phenylpropyl)acetamide 
• 1314640-76-0 C₂₈H₂₈F₃N₅O₂S 
• 91398-33-3 N-[5-(3-chloro-4-methoxy-benzenesulfonyl)-thiazol-2-yl]-acetamide 
• 91090-81-2 N-(5-benzenesulfonyl-thiazol-2-yl)-acetamide 
• 98068-34-9 N-[5-(2,5-dichloro-4-ethoxy-benzenesulfonyl)-thiazol-2-yl]-acetamide 
• 92645-38-0 N-[5-(4-butoxy-2-chloro-benzenesulfonyl)-thiazol-2-yl]-acetamide 
• 93864-10-9 N-[5-(3-chloro-4-propoxy-benzenesulfonyl)-thiazol-2-yl]-acetamide 
• 91688-59-4 N-[5-(3-bromo-4-methoxy-benzenesulfonyl)-thiazol-2-yl]-acetamide 

Relevant articles and documents

-

-

Thiazole compounds and methods of use

The invention relates to thiazole compounds of Formula I and Formula II and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.

Carbon substituted aminothiazole inhibitors of cyclin dependent kinases

Compounds of the formula and pharmaceutically acceptable salts thereof are provided.