72571-06-3

Basic information

• Product Name: 5-(4-BROMOPHENYL)-1,3-OXAZOLE
• Synonyms: 5-(4-BROMOPHENYL)-1,3-OXAZOLE;5-(4-BROMOPHENYL)OXAZOLE;1-Bromo-4-(1,3-oxazol-5-yl)benzene
• CAS NO: 72571-06-3
• Molecular Formula: C₉H₆BrNO
• Molecular Weight: 224.05
• Product Categories: Halides;Heterocycles
• Mol File: 72571-06-3.mol
• Article Data: 18

Chemical Properties

• Melting Point: 78-80°C
• Boiling Point: 315.8 °C at 760 mmHg
• Flash Point: 144.8 °C
• Appearance: /
• Density: 1.524 g/cm³
• Vapor Pressure: 0.000794mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 5-(4-BROMOPHENYL)-1,3-OXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-BROMOPHENYL)-1,3-OXAZOLE(72571-06-3)
• EPA Substance Registry System: 5-(4-BROMOPHENYL)-1,3-OXAZOLE(72571-06-3)

Safety Data

• Hazard Codes: T
• Statements: 36/37/38-25
• Safety Statements: 26-36/37/39-45
• HazardClass: IRRITANT
• Hazardous Substances Data: 72571-06-3(Hazardous Substances Data)

Usage

General Description

5-(4-Bromophenyl)-1,3-oxazole is a chemical compound with the molecular formula C9H6BrNO. It is a heterocyclic compound containing a five-membered oxazole ring with a bromophenyl substituent. 5-(4-BROMOPHENYL)-1,3-OXAZOLE is commonly used in pharmaceutical and agrochemical industries as a building block for the synthesis of various biologically active compounds such as medicinal drugs and pesticides. It is also utilized in chemical research and development processes for the creation of new chemical entities and materials. The presence of the bromine atom in the phenyl ring provides unique chemical and physical properties to this compound, making it a valuable intermediate in organic synthesis.

InChI:InChI=1/C9H6BrNO/c10-8-3-1-7(2-4-8)9-5-11-6-12-9/h1-6H

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 99-73-0 para-bromophenacyl bromide 
• 5467-72-1 α-amino-4-bromoacetophenone hydrochloride 
• 72571-04-1 ethyl [[2-(4-bromophenyl)-2-oxoethyl]amino]oxoacetate 
• 1122-91-4 4-bromo-benzaldehyde 
• 7099-87-8 4-bromophenylglyoxylic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 55605-27-1 (4-bromophenyl)methylenediacetate 
• 77287-34-4 formamide 
• 72571-05-2 ethyl 5-(4-bromophenyl)oxazole-2-carboxylate 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 1021919-20-9 5-(4-(trimethylstannyl)phenyl)oxazole 
• 96908-21-3 2-phenyl-5-(4-bromophenyl)-5-oxazole 
• 1170659-61-6 methyl 4-(5-(4-bromophenyl)oxazol-2-yl)benzoate 
• 1552273-99-0 5-(4-bromophenyl)-1-cyclopentyl-1H-imidazole 
• 1552274-14-2 5-(4-bromophenyl)-1-[2-(4-fluorophenyl)ethyl]-1H-imidazole 
• 1552274-28-8 1-cyclopropylmethyl-5-(4-bromophenyl)-1H-imidazole 
• 1145-12-6 5-([1,1'-biphenyl]-4-yl)oxazole 

Relevant articles and documents

INHIBITOR COMPOUNDS

The disclosure relates to heterocyclic compounds and methods for their preparation. The disclosure provides compounds that may have beneficial therapeutic activity in the treatment of a disease or condition mediated by excessive or otherwise undesirable Des1 and/or fibrotic activity.

PISTON FOR AN INTERNAL COMBUSTION ENGINE AND METHOD FOR PRODUCING THE PISTON FOR AN INTERNAL COMBUSTION ENGINE

The present invention relates to compounds of general formula (I), wherein A represents an optionally substituted heterocycle group, B represents an aryl or heteroaryl group and wherein X, R1, R2, R3, R4 and R5 are as defined in the description. Compounds of formula (I) are useful to destroy, inhibit, or prevent the growth or spread of cells, especially malignant cells, into surrounding tissues implicated in a variety of human and animal diseases.

Tandem cycloaddition-decarboxylation of α-keto acid and isocyanide under oxidant-free conditions towards monosubstituted oxazoles

An efficient method, tandem [3 + 2] cycloaddition-decarboxylation of α-keto acid and isocyanide promoted by copper salt, has been developed. Under oxidant-free conditions, a series monosubstituted oxazoles have been constructed. Different from the traditional application of α-oxo acids as acyl surrogates, the elegant approach herein ingeniously avoids consuming excess oxidants.