725738-51-2Relevant academic research and scientific papers
Multi-step application of immobilized reagents and scavengers: A total synthesis of epothilone C
Storer, R. Ian,Takemoto, Toshiyasu,Jackson, Philip S.,Brown, Dearg S.,Baxendale, Ian R.,Ley, Steven V.
, p. 2529 - 2547 (2004)
The total synthesis of the cytotoxic antitumour natural product epothilone C has provided a stage for the exploitation and further development of immobilized reagent methods. A stereoselective convergent synthetic strategy was applied, incorporating polymer-supported reagents, catalysts, scavengers and catch-and-release techniques to avoid frequent aqueous work-up and chromatographic purification.
