725738-52-3

Upstream product

• 98-88-4 benzoyl chloride 
• 725738-51-2 (3S)-3-hydroxy-2,2-dimethylpent-4-enyl benzoate 
• 725738-50-1 (3S)-2,2-dimethylpent-4-ene-1,3-diol 

Downstream Products

• 725738-53-4 (3S)-3,5-bis-(tert-butyldimethylsilyloxy)-2,2-dimethylpentyl benzoate 
• 187527-25-9 (-)-(5S)-5,7-bis{[tert-butyl(dimethyl)silyl]oxy}-4,4-dimethylheptan-3-one 

Relevant academic research and scientific papers

Multi-step application of immobilized reagents and scavengers: A total synthesis of epothilone C

The total synthesis of the cytotoxic antitumour natural product epothilone C has provided a stage for the exploitation and further development of immobilized reagent methods. A stereoselective convergent synthetic strategy was applied, incorporating polymer-supported reagents, catalysts, scavengers and catch-and-release techniques to avoid frequent aqueous work-up and chromatographic purification.