72641-13-5

Basic information

• Product Name: Tetrahydrofurfuryl methanesulfonate
• Synonyms: Tetrahydrofurfuryl methanesulfonate;(Tetrahydrofuran-2-yl)Methyl Methanesulfonate;ZFIIBAGNYNJVPU-UHFFFAOYSA-M
• CAS NO: 72641-13-5
• Molecular Formula: C₆H₁₂O₄S
• Molecular Weight: 180.22208
• Mol File: 72641-13-5.mol

Chemical Properties

• Boiling Point: 324.9°C at 760 mmHg
• Flash Point: 150.3°C
• Appearance: /
• Density: 1.245g/cm³
• Vapor Pressure: 0.000451mmHg at 25°C
• Refractive Index: 1.465
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Tetrahydrofurfuryl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Tetrahydrofurfuryl methanesulfonate(72641-13-5)
• EPA Substance Registry System: Tetrahydrofurfuryl methanesulfonate(72641-13-5)

Safety Data

• Hazardous Substances Data: 72641-13-5(Hazardous Substances Data)

Usage

Uses

Used in Coatings and Resins Industry:
THFMS is utilized as a solvent and stabilizer in the production of polyurethane coatings, resins, and adhesives, enhancing their performance and durability.
Used in Cleaning Products:
Tetrahydrofurfuryl methanesulfonate is used as an ingredient in cleaning products, where it contributes to their effectiveness and stability.
Used in Metalworking Fluids:
In the metalworking industry, THFMS is employed as a corrosion inhibitor and stabilizer, improving the longevity and performance of metalworking fluids.
Used as an Environmentally Friendly Solvent:
THFMS is recognized as a potential eco-friendly alternative to traditional solvents with known environmental and health hazards, making it an attractive option for industries seeking to reduce their environmental footprint.

InChI:InChI=1/C6H12O4S/c1-11(7,8)10-5-6-3-2-4-9-6/h6H,2-5H2,1H3

Upstream product

• 97-99-4 Tetrahydrofurfuryl alcohol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 119738-06-6 quizalofop-p-tefuryl 
• 33414-62-9 2-(tetrahydrofuran-2-yl)acetonitrile 
• 147240-13-9 (1E,7Z)-1-Phenyl-8-(toluene-4-sulfinyl)-octa-1,7-dien-3-ol 
• 147240-16-2 (Z)-1-Phenyl-6-(toluene-4-sulfinyl)-hex-5-en-1-ol 
• 147240-15-1 (2E,8Z)-9-(Toluene-4-sulfinyl)-nona-2,8-dien-4-ol 
• 69645-02-9 2-((p-tolylthio)methyl)tetrahydrofuran 

Relevant articles and documents

Synthesis and Characterization of bis(Tetrahydrofurfuryl) Ether

Despite the availability of a large number of alkyl tetrahydrofurfuryl ethers that have a wide range of applications, pure bis(tetrahydrofurfuryl) ether (BTHFE) has not been previously synthesized. Here, we report the synthesis of BTHFE (consisting of the RR, SS, and meso stereoisomers) at greater than 99 % purity from tetrahydrofurfuryl alcohol, using (tetrahydrofuran-2-yl)methyl methanesulfonate as an intermediate. Additionally, we demonstrate that BTHFE can be used as a non-volatile solvent in poly(3,4-propylenedioxythiophene)-based supercapacitors. Supercapacitor devices employing solutions of the ionic liquid 1-ethyl-3-methyl-imidizolium bis(trifluoromethylsulfonyl)imide in BTHFE display similar performances to those prepared by using the neat ionic liquid as an electrolyte, although solution-based devices exhibit a somewhat higher resistance.

One-pot preparation of Julia-Kocienski sulfides and sulfones from alcohols

A method for one-pot preparation of Julia-Kocienski sulfides and sulfones from alcohols and thiols is reported. A variety of primary alcohols were converted to the corresponding mesylates by methansulfonyl chloride and triethylamine in THF. After the reaction is complete, thiol (1 or 10) and either NaH or t-BuOK were added. The Julia-Kocienski sulfides 3, 9 and 11 were prepared by one-pot two steps procedure from alcohols in 76–96% yields (16 examples). Furthermore, after the sulfide formation, the reaction mixture was neutralized by p-toluenesulfonic acid and treated with H2O2 and ammonium molybdate in EtOH to give the Julia-Kocienski sulfones 4 in good yields except for trans-2-hexen-1-ol.

Method for the synthesis and purification of ethers

Methods of synthesizing and purifying ethers are described. The synthesis and purification are achieved using an etherification technique followed by one or two fractional distillations. The etherification utilizes an element having low work function properties. Examples of low work function elements include, but are not limited to, metals or their hydrides, such as sodium, lithium or potassium or some combination thereof. This technique yields ethers of greater than 90% purity.

Molybdenum oxide-mediated facile aliphatic nucleophilic fluorination

A facile aliphatic nucleophilic fluorination with cesium fluoride in the presence of molybdenum oxide as a catalyst has been demonstrated. Reactivity of molybdenum oxide in nanocrystal form was found to be chemoselective in the presence of water. Furthermore, the reaction is highly specific with alkyl sulfonate substrates.

HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS

6-substituted-3-substituted-3H-furo[2,3-d]pyrimidin-2-one and 6-substituted-2-substituted-furo[2,3-d]pyrimidine novel compounds are useful in the treatment of viral infection, in particular cytomegalovirus viral infection. The substituents are independently selected from alkyl, aryl, alkenyl and alkynyl. The preferred substituent at the 6 position is alkyl.

Pyrimidine derivatives as IL-8 receptor antagonists

Compounds containing the pyrimidine nucleus and their use to treat diseases and conditions related to inappropriate Interleukin-8 receptor activity are disclosed. The compounds are of the formula I In these compounds, Q is preferably unsubstituted and substituted heterocyclyl; U is usually hydrogen or fluorine; and V is preferably hydrogen, halogen, alkyl, —O—alkyl or —S-alkyl. A representative example is:

Insecticidal tetrahydrofuran-compound

A tetrahydrofuran-compound is disclosed herein which is represented by the formula (1) STR1 wherein each of X1 and X2 is a hydrogen atom or a methyl group, Y is a hydrogen atom or a carbonyl group substituted by a lower alkyl group (