728-22-3

Usage

InChI:InChI=1/C14H10ClNO2/c1-17-11-5-2-9(3-6-11)14-12-8-10(15)4-7-13(12)16-18-14/h2-8H,1H3

Upstream product

• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 7497-59-8 (2-amino-5-chlorophenyl)(4-methoxyphenyl)methanone 
• 100-00-5 4-chlorobenzonitrile 
• 104-47-2 p-methoxybenzylnitrile 

Downstream Products

• 7497-59-8 (2-amino-5-chlorophenyl)(4-methoxyphenyl)methanone 
• 784-41-8 2-amino-5-chloro-4'-hydroxy-benzophenone 
• 14427-37-3 2,8-dichloro-6,12-bis-(4-methoxy-phenyl)-dibenzo[b,f][1,5]diazocine 
• 121998-51-4 (5Z,11Z)-2,4,8,10-Tetrachloro-6,12-bis-(4-methoxy-phenyl)-dibenzo[b,f][1,5]diazocine 
• 51217-59-5 5-Chlor-2-amino-4'-methoxy-benzophenon-oxim 

Relevant academic research and scientific papers

Practical Synthesis of Benzimidazo[1,2- A[quinolines via Rh(III)-Catalyzed C-H Activation Cascade Reaction from Imidamides and Anthranils

We report a novel and practical one-pot Rh(III)-catalyzed strategy to construct benzimidazo[1,2-a]quinolines from readily available imidamides and anthranils. The cascade reaction proceeds via a C-H amination-cyclization-cyclization process in ionic liquid without any additives and possesses simple operation, moderate-to-high yield, and broad substrate scope features, which will provide the reference for the construction of biologically active fused benzimidazoles.

Catalyst-free cyclization of anthranils and cyclic amines: One-step synthesis of rutaecarpine

An efficient synthesis of a variety of quinazolinone derivatives via a direct cyclization reaction between commercially available anthranils and cyclic amines is described. The developed transformation proceeds with the merits of high step- and atom-efficiency, a broad substrate scope, and good to excellent yields, without additional catalysts, and offers a practical way for the preparation of rutaecarpine and its derivatives with structural diversity.

Synthesis of 3-Substituted 2,1-Benzisoxazoles by the Oxidative Cyclization of 2-Aminoacylbenzenes with Oxone

An efficient approach to the synthesis of 2,1-benzisoxazoles through direct construction of the N-O bond by the chemoselective oxidation of 2-aminoacylbenzenes with Oxone is described. This alternative methodology is characterized by its simple and transition-metal-free conditions and good functional group compatibility utilizing Oxone as a green oxidant instead of hypervalent iodine compounds. Moreover, this new procedure simplifies the number of steps compared to the previously reported procedure by circumventing the use of 2-azido-substituted aryl ketones.