72853-86-2

Upstream product

• 72853-84-0 Acetic acid 4-acetoxy-2-((1R,2S)-1,2,5,5-tetramethyl-1,2,3,4,5,6,7,8-octahydro-naphthalen-1-ylmethyl)-phenyl ester 
• 103476-92-2 (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan-2-ol 
• 564-20-5 (3aR)-(+)-sclareolide 
• 62890-98-6 2,5-dimethoxyphenylmagnesium bromide 
• 72853-81-7 Aureol 
• 72853-85-1 2-((1R,2S)-1,2,5,5-Tetramethyl-1,2,3,4,5,6,7,8-octahydro-naphthalen-1-ylmethyl)-benzene-1,4-diol 
• 77-78-1 dimethyl sulfate 

Relevant academic research and scientific papers

A six-step synthetic approach to marine natural product (+)-aureol

A concise synthetic approach to the marine natural product (+)-aureol has been achieved from readily available starting materials using obviously fewer steps in comparison to the related report in literature (6 steps versus 12 steps from (+)-sclareolide). Key steps of this protocol include a boron trifluoride-catalyzed domino 1,2-H and 1,2-methyl shifts and a nickel(II)-catalyzed cross-coupling reaction between an alkyl iodide and an aryl Grignard reagent.