72867-31-3Relevant academic research and scientific papers
Synthesis and characterization of Pd supported on methane diamine (propyl silane) functionalized Fe3O4 nanoparticles as a magnetic catalyst for synthesis of α-aminonitriles and 2-methoxy-2-phenylacetonitrile derivative via Strecker-t
Li, Qun,Liu, Wei,Mohammadnia, Majid,Song, Di,Sun, Mingzhe,Wu, Wei,Yan, Li
, (2021/09/18)
Pd supported on methane diamine (propyl silane) functionalized Fe3O4 magnetic nanoparticles as an organic–inorganic hybrid heterogeneous catalyst was fabricated and characterized by FT-IR, XRD, SEM, TEM, TGA, VSM, EDX, and ICP-AES te
Targeted development of hydrophilic porous polysulfonamide gels with catalytic activity
Alavinia, Sedigheh,Ghorbani-Vaghei, Ramin
, (2020/07/03)
We report the use of a template and functional monomers in the synthesis of three novel polysulfonamide gels with new architectures and functional groups. These mesoporous polysulfonamide gels were prepared by the condensation polymerization of benzene-1,3-disulfonyl chloride (as the main precursor), linear monomers, and cross-linkers (as variable precursors) in the presence of a silica template by a combination of sol-gel chemistry and the nanocasting technique. In this synthesis pathway, in situ polymerization onto the template surface led to the construction of a silica/polymer nanocomposite. Next, after removal of the template, the nanocomposite gels were transformed into mesoporous polysulfonamide nanospheres. After the physicochemical identification of the synthesized materials, functionalized polysulfonamides were used as reusable novel catalysts with high efficiency for the Strecker reaction under mild conditions. These polymers have Br?nsted/Lewis acid active sites, a mesoporous structure, and hydrogen bonding. Moreover, since these polymers are hydrogels that can absorb water, they can promote the Strecker reaction through chemical absorption of the generated water as a driving force. Overall, this article describes a novel synthesis procedure and application of porous polysulfonamide gels.
Cu/Ni-doped sulfated zirconium oxide immobilized on CdFe2O4 NPs: a cheap, sustainable and magnetically recyclable inorgano-catalyst for the efficient preparation of α-aminonitriles in aqueous media
Nasseri, Mohammad Ali,Ramezani-Moghadam, Simin,Kazemnejadi, Milad,Allahresani, Ali
, p. 4233 - 4256 (2020/07/08)
Abstract: A new multifunctional bimetallic nanocatalyst was prepared by immobilization of Cu/Ni-doped sulfated zirconium oxide on magnetic cadmium ferrite (CdFe2O4@SiO2@ZrO2/SO42?/Cu/Ni) and used as an efficient recyclable catalyst for one-pot as well as stepwise preparation of α-aminonitriles under mild conditions. The magnetic nanocatalyst was characterized by FTIR, TGA, VSM, XRD, EDX, FE-SEM, and TEM analyses. Also, the surface acidity of the catalyst was measured by pyridine adsorption assay. The catalyst possesses various active sites which could catalyst a variety of aromatic and aliphatic aldehydes to the corresponding α-amionitriles under moderate to high yields in the presence of aniline. Furthermore, transformation of ketones to the desired α-amionitriles and some bis-aminonitriles was also performed by this method. The catalyst could be readily recovered from the reaction mixture and reused for several times without significant loss of activity. Graphic abstract: A general and efficient method has been developed for transformation of a variety of aliphatic, aromatic aldehydes and ketones to the corresponding α-aminonitriles using a multifunctional recyclable CdFe2O4@SiO2@ZrO2/SO42?/Cu/Ni nanocatalyst.[Figure not available: see fulltext.]
Radical Rearrangement of Aryl/Alkylidene Malononitriles via Aza Michael Addition/Decynoformylation/Addition Sequence: An Access to α-Aminonitriles and α-Aminoamides
Bhoite, Shubhangi P.,Bansode, Ajay H.,Suryavanshi, Gurunath
, p. 14858 - 14865 (2020/12/02)
An efficient, safe, and environmentally friendly tertiary butyl hydrogen peroxide (TBHP)-mediated rearrangement of aryl/alkylidene malononitrile with anilines has been developed with in situ generation of HCN as the cyanide source for the synthesis of sub
Three-component solventless Strecker synthesis of α-aminonitriles catalysed by a renewable sulfonated nanoporous carbon catalyst (CMK-5-SO3H)
Zareyee, Daryoush,Rad, Ali Shokuhi,Ataei, Zahra,Javadi, Sayed Hossein,Khalilzadeh, Mohammad A.
, (2018/07/31)
The one-pot three-component synthesis of a variety of α-aminonitriles has been studied using a catalytic amount of a sulfonic acid-functionalized ordered nanoporous carbon catalyst, CMK-5-SO3H, at room temperature under solvent-free reaction co
Expeditious and efficient synthesis of Strecker's α-aminonitriles catalyzed by sulfated polyborate
Indalkar, Krishna S.,Khatri, Chetan K.,Chaturbhuj, Ganesh U.
supporting information, p. 2144 - 2148 (2017/05/10)
A straightforward, mild, efficient, and environmentally benign protocol for a three-component Strecker reaction of aldehydes or ketones, amines, and trimethylsilyl cyanide catalyzed by sulfated polyborate has been described to afford α-aminonitriles under solvent-free reaction conditions. The major advantages of the present method are excellent yields, shorter reaction time, simple experimental procedure, easy workup procedure, recyclability of the catalyst, solvent-free reaction conditions and ability to tolerate a variety of functional groups which gives economical as well as ecological rewards.
Dibutyltin dimethoxide-catalyzed cyano transfer to aldehydes and imines
Yanagisawa, Akira,Matsumoto, Takuya,Kushihara, Naoyuki,Yoshida, Kazuhiro
experimental part, p. 2918 - 2922 (2011/01/05)
A novel reaction involving cyano transfer from benzophenone cyanohydrin to aldehydes and imines was realized by using dibutyltin dimethoxide as a catalyst. Various cyanohydrins and α-amino nitriles were obtained in moderate to high yields by this reaction. Ketimines also showed remarkable reactivity as cyano acceptors under conventional reaction conditions. This catalytic reaction was further applied to a three-component condensation reaction of aldehydes, aniline, and benzophenone cyanohydrin in the presence of Drierite. Copyright
Water-mediated strecker reaction: An efficient and environmentally friendly approach for the synthesis of α-aminonitriles via a three-component condensation
Ramesh, Samikannu,Sivakumar, Kulanthaivel,Panja, Chiradeep,Arunachalam, Pirama Nayagam,Lalitha, Appaswami
experimental part, p. 3544 - 3551 (2011/01/12)
The synthesis of α-aminonitriles by a direct three component Strecker reaction has been achieved in water, which is found to be an inexpensive, non-toxic and eco-friendly reaction medium for the nucleophilic addition. This protocol is effective to a wide variety of substrates with different functional groups and does not require the use any other catalyst. Copyright Taylor & Francis Group, LLC.
One-pot three-component synthesis of α-aminonitriles using potassium hexacyanoferrate(II) as an eco-friendly cyanide source
Li, Zheng,Ma, Yuanhong,Xu, Jun,Shi, Jinghong,Cai, Hongfang
experimental part, p. 3922 - 3926 (2010/08/20)
An efficient and environmentally friendly method has been developed for the synthesis of α-aminonitriles via one-pot three-component condensation of carbonyl compounds, amines, and potassium hexacyanoferrate(II) in the presence of benzoyl chloride as a promoter. This protocol has the features of use of eco-friendly cyanide source, high yield, and simple work-up procedure.
Dibutyltin dibromide-catalyzed trimethylsilylcyanation of aldehydes and imines
Yanagisawa, Akira,Matsumoto, Takuya,Arai, Takayoshi,Yoshida, Kazuhiro
scheme or table, p. 336 - 337 (2010/01/16)
Dibutyltin dibromide efficiently catalyzes addition of tri-methylsilyl cyanide to aldehydes and aldimines. Various tri-methylsilylated cyanohydrins and α-aminonitriles are obtained in moderate to high yield by this method. Copyright
