7287-40-3Relevant articles and documents
Synthesis method 4 -cycloheximide methyl substituted benzofuran derivative
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Paragraph 0105-0109; 0119-0121; 0127-0129; 0135-0138; ..., (2021/11/27)
The invention provides a synthesis method of 4 - cycloheximide methyl substituted benzofuran derivatives. Belong to organic synthesis technical field. After the Lewis-methyl benzofuran 5 - carboxylic acid is obtained -2 -methoxy -3 -methylbenzofuran 5 - carboxylic acid and then subjected to a hydrolysis reaction under basic conditions to obtain -2 -methoxy -3 -methylbenzofuran 5 - carboxylic acid, and then reacted with -2 - aniline in the presence of a condensing agent and a base to obtain -3 -methoxy R - methyl 5 -2 - R -phenyl benzofuran -3 - N formamide. After demethyl reaction 5 - hydroxyl -2 - methyl - N-R -phenyl benzofuran -3 - formamide was obtained, and finally, formaldehyde was added. Of the cycloheximide Mannich resulted in the final product.
Highly efficient benzodifuran based ruthenium sensitizers for thin-film dye-sensitized solar cells
Bosiak, Mariusz J.,Rakowiecki, Marcin,Wolan, Andrzej,Szlachta, Jolanta,Stanek, Edyta,Cycoń, Dawid,Skupień, Krzysztof
, p. 79 - 87 (2015/06/08)
The synthesis of 4,4′-dibenzodifuran-2,2′-bipyridine derivatives as ligands of organic ruthenium dyes for DSSC applications is described. Two new heteroleptic ruthenium complexes have been prepared and compared with commercially available N719 and Z907 dyes, using dip dyeing and flow dyeing methods in large area testing cells prepared for industrial purposes. The newly synthesized dyes revealed higher solar-to-electric energy conversion efficiency (η), measured at the AM1.5G conditions, up to 21% compared to N719 and up to 46% compared to Z907, and external quantum efficiency of 53%. These results can be explained by enhanced light-harvesting of the benzodifuran moiety of the dyes that is related to photocurrent.
Synthesis, discovery and preliminary SAR study of benzofuran derivatives as angiogenesis inhibitors
Chen, Yuan,Chen, Shaopeng,Lu, Xin,Cheng, Hao,Ou, Yingyong,Cheng, Huimin,Zhou, Guo-Chun
scheme or table, p. 1851 - 1854 (2009/11/30)
A series of benzofuran derivatives were synthesized and evaluated against HUVEC proliferation. Among these compounds, compound 32 exhibited good inhibitory activity and remarkable selectivity to HUVEC. Our current data suggested that array order of methyl, acrylate and carboxylate groups in benzofuran scaffold is the basic requirement for inhibitory activity against HUVEC proliferation. These results demonstrated that benzofuran scaffold represents a promising structural core to discover a new class of active and selective angiogenesis inhibitors.