729-39-5Relevant academic research and scientific papers
Decarboxylative Hydroxylation of Benzoic Acids
Ritter, Tobias,Su, Wanqi,Xu, Peng
supporting information, p. 24012 - 24017 (2021/10/06)
Herein, we report the first decarboxylative hydroxylation to synthesize phenols from benzoic acids at 35 °C via photoinduced ligand-to-metal charge transfer (LMCT)-enabled radical decarboxylative carbometalation. The aromatic decarboxylative hydroxylation is synthetically promising due to its mild conditions, broad substrate scope, and late-stage applications.
Transition-Metal-Free DMAP-Mediated Aromatic Esterification of Amides with Organoboronic Acids
Guo, Jiarui,Liu, Lantao,Wang, Tao,Wang, Yanqing,Xu, Kai,Zhang, Yuheng
supporting information, p. 3274 - 3277 (2021/06/26)
A new, transition-metal-free, effective method for aromatic esterification of amides with organoboronic acids has been developed. A wide range of benzoate derivatives were obtained with yields ranging from moderate to good. The catalytic reaction shows a broad substrate scope and excellent functional group tolerance. Conceptually, DMAP mediates the reaction and is crucial for this transformation.
N-heterocyclic carbene-catalyzed aerobic oxidative direct esterification of aldehydes with organoboronic acids
Meng, Jing-Jing,Gao, Min,Wei, Yu-Ping,Zhang, Wen-Qin
experimental part, p. 872 - 875 (2012/07/03)
A simple procedure affording benzoates through a NHC-catalyzed aerobic oxidative esterification of aldehydes with organoboronic acids has been disclosed. This process allows access to a wide variety of aromatic esters in good to excellent yields under simple, efficient, and sustainable reaction conditions (see scheme).
Palladium-catalyzed aromatic esterification of aldehydes with organoboronic acids and molecular oxygen
Qin, Changming,Wu, Huayue,Chen, Jiuxi,Liu, Miaochang,Cheng, Jiang,Su, Weike,Ding, Jinchang
supporting information; experimental part, p. 1537 - 1540 (2009/04/07)
A palladium-catalyzed aromatic esterification reaction of aldehydes with arylboronic acids under an air atmosphere was achieved. This reaction tolerates many functional groups and provides aryl benzoate derivatives with yields ranging from moderate to good. Dioxygen takes part in the reaction and is crucial for this transformation.
NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS
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Example P424, (2010/11/24)
A pharmaceutical useful as a therapeutic agent and a preventive agent for hyperlipemia, and a pharmaceutical useful as a therapeutic agent and a preventive agent for hepatic disorders associated with cholestasis, particularly, primary biliary cirrhosis an
The synthesis of 4-(4-[11C]methoxyphenyl)-5-fluoro-2-hydroxyphenyl)-methylene-aminobutyric acid, as a potential radioligand for the GABA receptor in the brain
De Vos,Slegers
, p. 643 - 652 (2007/10/02)
A procedure for the synthesis of 4-(4-[11C]methoxyphenyl)-(5fluoro-2-hydroxyphenyl)-methylene-aminobutyric acid has been developed. The production entailed a O-methylation of 5-fluoro-2-hydroxy-4'-hydroxybenzophenone with cyclotron produced [s
