72908-00-0 Usage
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A chemical compound with a specific molecular structure.
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A naturally occurring chemical compound derived from plant roots, widely known for its insecticidal properties.
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The compound is derived from the roots of plants, indicating its natural origin and potential for extraction and use.
4. Insecticidal properties
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Rotenone disrupts the mitochondrial electron transport chain in insects, leading to their death, making it an effective insecticide and pesticide.
5. Neurotoxin potential
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Rotenone has been studied for its potential as a neurotoxin, indicating possible effects on the nervous system.
6. Parkinson's disease research
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The compound plays a role in research related to Parkinson's disease, possibly due to its neurotoxin potential and effects on the brain.
7. Health risks for humans
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Rotenone has been linked to negative health effects in humans, such as respiratory issues and skin irritation.
8. Carcinogenicity
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The Environmental Protection Agency classifies rotenone as a possible carcinogen, meaning it may have the potential to cause cancer.
9. Safety precautions
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It is important to handle and use rotenone with caution, following safety guidelines to minimize potential health risks and adverse effects.
Origin
Roots of certain plants
Check Digit Verification of cas no
The CAS Registry Mumber 72908-00-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,9,0 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72908-00:
(7*7)+(6*2)+(5*9)+(4*0)+(3*8)+(2*0)+(1*0)=130
130 % 10 = 0
So 72908-00-0 is a valid CAS Registry Number.
72908-00-0Relevant academic research and scientific papers
New cyclopenta[a]naphthalene derivatives: Synthesis of 2-(carbamylmethyl)-8-hydroxy-3H-cyclopenta[a]naphthalene as a possible deoxyribonucleic acid binding agent
Kundu
, p. 512 - 516 (2007/10/02)
8-Methoxy-1-oxo-2,3-dihydro-1H-cyclopental[a]naphthalene (4) was converted to the oxalyl derivative (7) by treatment with diethyl oxalate in the presence of sodium ethoxide. Compound 7 in the form of the sodium salt was alkylated with ethyl bromoacetate in DMF to 2-(carbethoxymethyl)-8-methoxy-1-oxo-2,3-dihydro-1H-cyclopenta[a]naphthalene (8). Treatment of 8 with methanolic ammonia yielded the corresponding amide (9). Dealkylation of 8 with 48% HBr and subsequent esterification gave compound 10. Ammonolysis of 10 led to the amide 11, which after reduction and subsequent dehydration of the reduced product afforded the desired compound, 2-(carbamylmethyl)-8-hydroxy-3H-cyclopenta[a]naphthalene (2). Compound 2 was found to be mildly growth inhibitory to L1210 and CCRF-CEM leukemic cells in culture. From thermal transition temperature studies, compound 2 was found to bind to calf thymus DNA and the poly(deoxyribonucleotides), e.g., poly(dG)-poly(dC), poly(dG-dC), poly(dA)-poly(dT), and poly (dA-dT).
