72908-01-1 Usage
Uses
Used in Pharmaceutical Industry:
2-(carbamylmethyl)-8-hydroxy-3H-cyclopenta(a)naphthalene is used as a potential therapeutic agent for various applications due to its complex structure and potential interactions with biological molecules. Its ability to bind with proteins and enzymes may offer opportunities for the development of new drugs targeting specific diseases.
Used in Chemical Research:
In the field of chemical research, 2-(carbamylmethyl)-8-hydroxy-3H-cyclopenta(a)naphthalene serves as a subject of study for understanding the properties and reactivity of complex organic compounds. Its unique structure may provide insights into the synthesis of novel compounds and the exploration of new chemical reactions.
Used in Material Science:
2-(carbamylmethyl)-8-hydroxy-3H-cyclopenta(a)naphthalene may be utilized in material science for the development of new materials with specific properties. The cyclopenta(a)naphthalene ring system could contribute to the compound's stability and potentially influence its electronic, optical, or mechanical characteristics, making it suitable for applications in advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 72908-01-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,9,0 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 72908-01:
(7*7)+(6*2)+(5*9)+(4*0)+(3*8)+(2*0)+(1*1)=131
131 % 10 = 1
So 72908-01-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NO2/c16-15(18)7-9-5-11-2-1-10-3-4-12(17)8-14(10)13(11)6-9/h1-4,6,8,17H,5,7H2,(H2,16,18)
72908-01-1Relevant academic research and scientific papers
New cyclopenta[a]naphthalene derivatives: Synthesis of 2-(carbamylmethyl)-8-hydroxy-3H-cyclopenta[a]naphthalene as a possible deoxyribonucleic acid binding agent
Kundu
, p. 512 - 516 (2007/10/02)
8-Methoxy-1-oxo-2,3-dihydro-1H-cyclopental[a]naphthalene (4) was converted to the oxalyl derivative (7) by treatment with diethyl oxalate in the presence of sodium ethoxide. Compound 7 in the form of the sodium salt was alkylated with ethyl bromoacetate in DMF to 2-(carbethoxymethyl)-8-methoxy-1-oxo-2,3-dihydro-1H-cyclopenta[a]naphthalene (8). Treatment of 8 with methanolic ammonia yielded the corresponding amide (9). Dealkylation of 8 with 48% HBr and subsequent esterification gave compound 10. Ammonolysis of 10 led to the amide 11, which after reduction and subsequent dehydration of the reduced product afforded the desired compound, 2-(carbamylmethyl)-8-hydroxy-3H-cyclopenta[a]naphthalene (2). Compound 2 was found to be mildly growth inhibitory to L1210 and CCRF-CEM leukemic cells in culture. From thermal transition temperature studies, compound 2 was found to bind to calf thymus DNA and the poly(deoxyribonucleotides), e.g., poly(dG)-poly(dC), poly(dG-dC), poly(dA)-poly(dT), and poly (dA-dT).
