7295-46-7

Usage

Uses

Used in Organic Synthesis:
4-BROMOPENTANOPHENONE is used as a building block for the synthesis of pharmaceuticals and biologically active compounds, leveraging its unique structural features and reactivity to contribute to the development of novel molecules with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-BROMOPENTANOPHENONE is utilized as a key intermediate in the preparation of drugs, enhancing the discovery and development of new therapeutic agents by providing a versatile starting material for chemical modifications and reactions.
Used as a Reagent in Chemical Reactions:
4-BROMOPENTANOPHENONE serves as a reagent in various chemical reactions, particularly in the modification of organic molecules. Its presence allows for the alteration of molecular properties, which can be crucial for optimizing the pharmacological activity and selectivity of target compounds.
Used in Drug Discovery and Development:
Due to its potential applications and reactivity, 4-BROMOPENTANOPHENONE is employed in drug discovery and development processes. It aids in the exploration of new chemical entities and the enhancement of existing drug molecules, contributing to the advancement of pharmaceutical research and innovation.

InChI:InChI=1/C12H15BrO/c1-2-3-4-5-12(14)10-6-8-11(13)9-7-10/h6-9H,2-5H2,1H3

Upstream product

• 71434-62-3 (+/-)-p-bromophenyl-1-hexanol 
• 108-86-1 bromobenzene 
• 142-61-0 Hexanoyl chloride 
• 1340546-31-7 diisopropyl 1-(4-bromobenzoyl)hydrazine-1,2-dicarboxylate 
• 693-25-4 n-pentylmagnesium bromide 
• 19920-80-0 1-(4-bromophenyl)cyclohexan-1-ol 
• 1122-91-4 4-bromo-benzaldehyde 
• 693-02-7 hex-1-yne 
• 62-53-3 aniline 
• 190649-11-7 1-bromo-4-(hex-1-yn-1-yl)benzene 

Downstream Products

• 91800-85-0 α-<4-Brom-phenyl>-hexylamin 
• 431041-28-0 (-)-(S)-1-p-bromophenyl-1-hexanol 
• 431041-21-3 (-)-[(S)-1-(4-bromophenyl)hexyloxy]tert-butyldimethylsilane 
• 431041-23-5 (+)-(3'aS,4'S,5'R,6'aR)-[4'-[4-((S)-1''-(tert-butyldimethylsilanyloxy)hexyl)phenyl]-1',6'a,6',3'a-tetrahydro-5,5-dimethylspiro[1,3-dioxane-2,2']]pentalen-5'-ol 
• 431041-25-7 (-)-(3aS,4S,5R,6aR)-5-hydroxy-4-{4-[(S)-1'-(tert-butyldimethylsilanyloxy)hexyl]phenyl}-5-[tert-butyldimethylsilanyloxy]hexahydropentalen-2-one 
• 1006603-37-7 C₁₇H₂₅BrO₂ 
• 23703-22-2 1-bromo-4-n-hexylbenzene 
• 1123795-07-2 C₄₂H₄₂O₂ 
• 1116113-69-9 C₂₀H₃₃BrO 
• 1005164-68-0 C₂₄H₃₀ClNO₄S 
• 1065644-37-2 2,6-bis[2-(4-hexylphenyl)ethynyl]anthracene 
• 79887-11-9 4-hexylphenylacetylene 
• 259139-06-5 1-n-hexyl-4-(trimethylsilylethynyl)benzene 
• 38237-76-2 1-(4-aminophenyl)-hexan-1-one 

Relevant academic research and scientific papers

Preparation method of aryl ketone compound

The invention provides a preparation method of an aryl ketone compound, and belongs to the technical field of compound synthesis. The method comprises the following steps: under the action of a silver catalyst and water, carrying out reaction on aryl alkyne with a structure as shown in a formula 1 in a solvent at 60-120 DEG C for 12-48 hours, and separating and purifying a product after the reaction is finished, so as to obtain the single aryl ketone compound with a structure as shown in a formula I, the raw materials are easy to obtain, the experimental operation is simple, the yield of the prepared single aryl ketone compound is good, and gram-scale experiments can be carried out.

Iron-Catalyzed C-C Single-Bond Cleavage of Alcohols

An iron-catalyzed deconstruction/hydrogenation reaction of alcohols through C-C bond cleavage is developed through photocatalysis, to produce ketones or aldehydes as the products. Tertiary, secondary, and primary alcohols bearing a wide range of substituents are suitable substrates. Complex natural alcohols can also perform the transformation selectively. A investigation of the mechanism reveals a procedure that involves chlorine radical improved O-H homolysis, with the assistance of 2,4,6-collidine.

Chiral Dibenzopentalene-Based Conjugated Nanohoops through Stereoselective Synthesis

Conjugated nanohoops allow to investigate the effect of radial conjugation and bending on the involved π-systems. They can possess unexpected optoelectronic properties and their radially oriented π-system makes them attractive for host–guest chemistry. Be

NOVEL COMPOUND AND SEMICONDUCTOR MATERIAL CONTAINING THE SAME

PROBLEM TO BE SOLVED: To provide a novel compound exhibiting n type semiconductor property with both of stability in air and solvent solubility, and a semiconductor element exhibiting stability in air and n type semiconductor property by using the compoun

Application of diphenylamino biphenyl carbonyl compounds to photocuring formula system

The invention relates to the technical field of novel material organic chemicals, in particular to a diphenylamino biphenyl carbonyl compound shown as a formula (I), a purpose of the compound as a radiation curing photoinitiator, and application purposes

Acyl hydrazides as acyl donors for the synthesis of diaryl and aryl alkyl ketones

In this communication we describe a novel strategy for the formation of valuable diaryl and aryl alkyl ketones from acyl hydrazides. A wide variety of ketones are prepared and the mild reaction conditions allow for the use of a range of functionalities, especially in the synthesis of diaryl ketones.

Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides

A number of structural analogues of the known toxicant para- aminopropiophenone (PAPP) have been prepared and evaluated for their capacity to induce methemoglobinemia - with a view to their possible application as humane pest control agents. It was found that an optimal lipophilicity for the formation of methemoglobin (metHb) in vitro existed for alkyl analogues of PAPP (aminophenones 1-20; compound 6 metHb% = 74.1 ± 2). Besides lipophilicity, this structural sub-class suggested there were certain structural requirements for activity, with both branched (10-16) and cyclic (17-20) alkyl analogues exhibiting inferior in vitro metHb induction. Of the four candidates (compounds 4, 6, 13 and 23) evaluated in vivo, 4 exhibited the greatest toxicity. In parallel, aminophenone bioisosteres, including oximes 30-32, sulfoxide 33, sulfone 34 and sulfonamides 35-36, were found to be inferior metHb inducers to lead ketone 4. Closer examination of Hammett substituent constants suggests that a particular combination of the field and resonance parameters may be significant with respect to the redox mechanisms behind PAPPs metHb toxicity.

Solution processable symmetric 4-alkylethynylbenzene end-capped anthracene derivatives

New candidates composed of anthracene and 4-alkylethynylbenzene end-capped oligomers for OTFTs were synthesized under Sonogashira coupling reaction conditions. All oligomers were characterized by FT-IR, mass, UV-visible, and PL emission spectrum analyses, cyclic voltammetry (CV), differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), 1H-NMR, and 13C-NMR. Investigation of their physical properties showed that the oligomers had high oxidation potential and thermal stability. Thin films of DHPEAnt and DDPEAnt were characterized by spin coating them onto Si/SiO 2 to fabricate top-contact OTFTs. The devices prepared using DHPEAnt and DDPEAnt showed hole field-effect mobilities of 4.0 × 10-3 cm2/Vs and 2.0 × 10-3 cm2/Vs, respectively, for solution-processed OTFTs.

Synthesis, optical, and electronic properties of soluble poly-p-phenylene oligomers as models for molecular wires

A homologous series of soluble poly-p-phenylenes containing up to eight phenylene moieties(pp2-pp8)with branched iso-alkyl(or bis-n-alkylmethyl)groups has been synthesized and the structure-property relationship with regards to various optical and electronic properties established. All electronic and optoelectronic properties of poly-p-phenylenes followed a 1/n relationship(where n is number of phenylene moieties)with the increasing number of phenylene moieties. The low-energy electronic transition of the pp2-PP7 cation radicals, generated either by laser-flash photolysis or by chemical oxidation,varied as well according to the inverse(1/n)relationship. The observed inverse relationship of all measured electronic and optoelectronic prope rties against the increasing number of phenylene units in various ppn's, as well as X-ray crystallography of both neutral and a cation-radical salt of a representative tetra-p-phenylene oligomer allows us to demonstrate that the effective conjugation length in poly-p-phenylenes is, in part, controlled by the increasing number of interactions of ortho hydrogens which may prevent simultaneous planarization of the continuous arrays of a large number of phenylene moieties.

Duplexiphane: A polyaromatic receptor containing two adjoined Δ-shaped cavities for an efficient hopping of a single silver cation

A simple synthesis of a polyaromatic receptor (i.e., duplexiphane) containing two adjoined Δ-shaped cavities is accomplished via an intramolecular (double) McMurry coupling, and its structure is established by X-ray crystallography. The binding of silver