73018-98-1

Usage

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx.

InChI:InChI=1/C3H7N3O2/c4-6-5-1-3(8)2-7/h3,7-8H,1-2H2

Upstream product

• 96-24-2 3-monochloro-1,2-propanediol 
• 25261-56-7 4-(azidomethyl)-2,2?dimethyl-1,3-dioxolane 
• 556-52-5 oxiranyl-methanol 

Downstream Products

• 96800-65-6 <3-(4-acetylphenyl)-2-oxo-5-oxazolidinyl>methyl azide 
• 1044255-51-7 C₁₈H₂₂N₄O₅S 
• 1015479-91-0 4-(azidomethyl)-2-(4-chlorophenyl)-1,3-dioxolane 
• 1015479-90-9 4-(azidomethyl)-2-(3-chlorophenyl)-1,3-dioxolane 
• 1015479-89-6 4-(azidomethyl)-2-(2-chlorophenyl)-1,3-dioxolane 
• 1015479-94-3 4-(azidomethyl)-2-(3-methoxyphenyl)-1,3-dioxolane 
• 168431-73-0 1-azido-3-(p-toluenesulfonyloxy)propan-2-ol 
• 367925-74-4 5-azidomethyl-3-phenyl-1,3-oxazolidin-2-one 

Relevant academic research and scientific papers

Turning Off Transcription with Bacterial RNA Polymerase through CuAAC Click Reactions of DNA Containing 5-Ethynyluracil

Copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) click reaction in the major groove of DNA containing 5-ethynyluracil (UE) with azides was used for turning off sequence-specific protein–DNA interactions. The concept was first demonstrated

COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS

This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.

Hydrophilic Clicked 2,6-Bis-Triazolyl-pyridines Endowed with High Actinide Selectivity and Radiochemical Stability: Toward a Closed Nuclear Fuel Cycle

There is still an evident need for selective and stable ligands able to separate actinide(III) from lanthanide(III) metal ions in view of the treatment of the accumulated radioactive waste and of the recycling of minor actinides. We have herein demonstrated that hydrophilic 2,6-bis-Triazolyl-pyridines are able to strip all actinides in all the different oxidation states from a diglycolamide-containing kerosene solution into an acidic aqueous phase. The ascertained high actinide selectivity, efficiency, extraction kinetics, and chemical/radiolytic stability spotlight this hydrophilic class of ligands as exceptional candidates for advanced separation processes fundamental for closing the nuclear fuel cycle and solving the environmental issues related to the management of existing nuclear waste.

IONIC LIQUIDS, AND THE METHOD FOR PREPARING THE SAME AND THE METHOD FOR SYNTHESIZING 2-AZIDOALCOHOL USING THE SAME

The present invention provides a method of preparing a room temperature ionic liquid (RTIL), comprising: a precursor forming step of forming a trimesylate by using glycerol as a starting material; and a step of obtaining a reactant by mixing the precursor

Design, synthesis and shape evaluation of cerium iron oxide nanorods for an epoxide opening reaction through azide addition

Uniform nanorod structured Ce1-xFexO2 has been synthesized through a simple urea hydrolysis method without any surfactant. The prepared nanorods of Ce0.75Fe0.25O2 are well clear and uniform

Towards engineering of self-assembled nanostructures using non-ionic dendritic amphiphiles

Engineering nanostructures of defined size and morphology is a great challenge in the field of self-assembly. Herein we report on the formation of supramolecular nanostructures of defined morphologies with subtle structural changes for a new series of dendritic amphiphiles. Subsequently, we studied their application as nanocarriers for guest molecules.

Glycerol functionalized imidazolium tri-cationic room temperature ionic liquids: Synthesis, properties and catalytic performance for 2-azidoalcohol synthesis from epoxide

Imidazolium based tri-cationic room temperature ionic liquid (RTILs) were synthesized and characterized, and their physicochemical properties such as thermal stability, viscosities and solubility were investigated. These ionic liquids exhibited excellent

COMPOUND HAVING FLUORESCENT CHROMOPHORE, ION CONCENTRATION SENSOR INCLUDING COMPOUND, REAGENT INCLUDING COMPOUND, REAGENT KIT PROVIDED WITH REAGENT, PRECURSOR OF COMPOUND, AND METHOD FOR SYNTHESIZING COMPOUND

A compound of the present invention comprises a triazapentalene backbone represented by the general formula 1 below as a fluorescent chromophore.

Discovery of chemoselective and biocompatible reactions using a high-throughput immunoassay screening

An immunoassay-based method was used to screen numerous combinations of dipoles and dipolarophiles for their ability to undergo chemoselective and biocompatible [3+2] cycloaddition reactions. The approach fulfills most of the requirements of the click concept and led to the discovery of a copper-catalyzed reaction that generates pyrazoles from sydnone and alkyne reagents. Copyright

One-pot synthesis of highly fluorescent 2,5-disubstituted-1,3a,6a- triazapentalene

A one-pot synthetic method was established for the preparation of 2,5-disubstituted-1,3a,6a-triazapentalenes. The fluorescence observation of the synthetic 2,5-disubstituted-1,3a,6a-triazapentalenes revealed that the introduction of a substituent at the C