73030-04-3

Basic information

• Product Name: acetonyl methoxatin
• Synonyms: acetonyl methoxatin
• CAS NO: 73030-04-3
• Molecular Formula: C17H12 N2 O9
• Molecular Weight: 388.29
• Mol File: 73030-04-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 1012.3°C at 760 mmHg
• Flash Point: 566°C
• Appearance: /
• Density: 1.778g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.732
• CAS DataBase Reference: acetonyl methoxatin(CAS DataBase Reference)
• NIST Chemistry Reference: acetonyl methoxatin(73030-04-3)
• EPA Substance Registry System: acetonyl methoxatin(73030-04-3)

Safety Data

• Hazardous Substances Data: 73030-04-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H12N2O9/c1-5(20)4-17(28)12-10(6(14(22)23)2-9(19-12)16(26)27)11-7(13(17)21)3-8(18-11)15(24)25/h2-3,18,28H,4H2,1H3,(H,22,23)(H,24,25)(H,26,27)

Upstream product

• 67-64-1 acetone 
• 78939-39-6 5-methoxy-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester 
• 78939-37-4 4-oxo-pent-2-enedioic acid dimethyl ester 
• 78939-35-2 6-Formylamino-5-methoxy-1H-indole-2-carboxylic acid methyl ester 
• 148728-48-7 3-bromo-2-oxopentane-1,5-dioic acid dimethyl ester 
• 13192-04-6 dimethyl 2-ketoglutarate 
• 78891-38-0 dimethyl 7,8-dimethoxy-6-<3-methoxy-3-oxo-2-(phenylhydrazono)propyl>-5-nitro-2,4-quinolinedicarboxylate 
• 78891-39-1 trimethyl 4,5-dimethoxy-1H-pyrrolo<2,3-f>quinoline-2,7,9-tricarboxylate 
• 74447-88-4 trimethyl 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate 
• 80721-44-4 3-Nitro-4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester 
• 80721-46-6 3-Diazo-4,5-dioxo-4,5-dihydro-3H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester 
• 80721-45-5 3-Amino-4,5-dihydroxy-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester 
• 80721-47-7 4,5-Dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester 
• 72909-34-3 pyrroloquinoline quinone 

Relevant articles and documents

LIFE-EXTENDING AGENT, LIFE EXTENSION METHOD USING THE LIFE-EXTENDING AGENT, NOVEL DUAL OXIDASE ACTIVATOR, METHOD FOR ACTIVATING DUAL OXIDASE, PRODUCTION OF LIFE-EXTENDING AGENT, AND PRODUCTION OF DUAL OXIDASE ACTIVATOR

The present invention provides a life-extending agent comprising pyrroloquinoline quinone and/or a derivative of the pyrroloquinoline quinone.

Synthesis of the Bacterial Coenzyme Methoxatin

The details of a total synthesis of methoxatin (1), the coenzyme of several bacterial alcohol dehydrogenases, are presented.Methoxatin has been prepared in 13 steps by starting from 2,3-dimethoxytoluene.The successful synthetic strategy for construction of the coenzyme used a Pfitzinger synthesis for preparation of the quinoline dicarboxylic acid portion of 1 and an "umpolung" variation of the Reissert indole synthesis for annulation of the remaining pyrrole ring.

Total Synthesis of Methoxatin, the Coenzyme of Methanol Dehydrogenase and Glucose Dehydrogenase

The first total synthesis of the bacterial coenzyme methoxatin has been successfully completed starting from readily available 2,3-dimethoxytoluene.