7314-43-4

Usage

Uses

Used in Pharmaceutical Development:
AMINO-(3-METHOXY-PHENYL)-ACETIC ACID is used as a potential candidate in pharmaceutical development for its structural similarity to natural amino acids, which allows it to interact with biological systems. This characteristic makes it a valuable component in the creation of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, AMINO-(3-METHOXY-PHENYL)-ACETIC ACID is used as a precursor. Its unique structure and functional groups contribute to the synthesis of various organic compounds, making it a versatile building block for chemical reactions.
Used in Research and Development:
AMINO-(3-METHOXY-PHENYL)-ACETIC ACID is utilized in research and development settings to explore its properties and potential applications further. Its intriguing chemical structure and interactions with biological systems make it a subject of interest for scientists looking to innovate in the fields of medicine and chemistry.

InChI:InChI=1/C9H11NO3/c1-13-7-4-2-3-6(5-7)8(10)9(11)12/h2-5,8H,10H2,1H3,(H,11,12)

Upstream product

• 26767-10-2 2-(3-methoxyphenyl)glyoxylic acid 
• 626-20-0 3-methoxystyrene 
• 32345-63-4 1-(3-methoxyphenyl)-1,2-ethanediol 
• 86215-57-8 bromo-(3-methoxy-phenyl)-acetic acid methyl ester 
• 591-31-1 3-methoxy-benzaldehyde 
• 271583-61-0 2-(N-benzylamino)-2-(3-methoxyphenyl)acetonitrile 
• 271583-24-5 benzylamino-(3-methoxy-phenyl)-acetic acid 
• 129592-95-6 methyl N-(trifluoroacetyl)-2-amino-2-(3-methoxyphenyl)acetate 

Downstream Products

• 125190-66-1 N-(benzyloxycarbonyl)-(R,S)-(3-methoxyphenyl)glycine 
• 848564-51-2 [3-(1-{methyl-[(4-trifluoromethyl-phenyl)-acetyl]-amino}-2-pyrrolidin-1-yl-ethyl)-phenoxy]-acetic acid tert-butyl ester 
• 261524-04-3 N-[1-(3-hydroxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-2-(4-trifluoromethyl-phenyl)-acetamide 
• 261524-02-1 N-[1-(3-methoxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-2-(4-trifluoromethyl-phenyl)-acetamide 
• 261524-26-9 [1-(3-methoxy-phenyl)-2-oxo-2-pyrrolidin-1-yl-ethyl]-carbamic acid methyl ester 
• 125190-67-2 [1-(3-Methoxy-phenyl)-2-pyrrolidin-1-yl-ethyl]-methyl-amine 
• 31932-87-3 D-α-amino-m-hydroxyphenylacetic acid 

Relevant academic research and scientific papers

Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine

The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.

A facile synthesis of substituted phenylglycines

A convenient scaleable process for the preparation of substituted phenylglycines 2 by a modified Strecker reaction is described. Bisulfite- mediated addition of benzylamine and cyanide anion to substituted benzaldehydes 3 gave the aminonitriles 4 which were hydrolysed in two steps to the N-protected amino acid 1. Debenzylation using catalytic transfer hydrogenation gave the title compounds in good yield.

7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids

Certain 7-acylamido-3-(1-carboxy-loweralkyl-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids and their salts and easily hydrolyzed esters of the 4-carboxyl group were synthesized and found to be potent antibacterial agents which exhibited good aqueous solubility. In a preferred embodiment the 7-substituent was 2'-aminomethylphenylacetamido.