73178-07-1

Basic information

• Product Name: -p-chlorobenzene
• Synonyms: -p-chlorobenzene
• CAS NO: 73178-07-1
• Molecular Weight: 426.659
• Mol File: 73178-07-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: -p-chlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: -p-chlorobenzene(73178-07-1)
• EPA Substance Registry System: -p-chlorobenzene(73178-07-1)

Safety Data

• Hazardous Substances Data: 73178-07-1(Hazardous Substances Data)

Upstream product

• 52207-56-4 1-chloro-4-iodosylbenzene 
• 104-15-4 toluene-4-sulfonic acid 
• 6973-73-5 4-chloro-1-(diacetoxyiodo)benzene 
• 637-87-6 1-Chloro-4-iodobenzene 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 85925-65-1 (4-chlorophenyl)-2-(5-methylfuryl)iodonium iodide 
• 73177-97-6 -o-toluene 
• 27126-76-7 [hydroxy(tosyloxy)iodo]benzene 

Downstream Products

• 58506-46-0 (p-chlorophenyl)(2-thienyl)iodonium tosylate 
• 91228-68-1 (p-chlorophenyl)(5-methyl-2-thienyl)iodonium tosylate 
• 85925-59-3 Toluene-4-sulfonate(4-chloro-phenyl)-furan-2-yl-iodonium; 
• 91228-72-7 (p-chlorophenyl)(3-methyl-2-thienyl)iodonium tosylate 
• 85925-28-6 Toluene-4-sulfonate(4-chloro-phenyl)-(5-trimethylsilanyl-furan-2-yl)-iodonium; 
• 1382354-96-2 (2-(2-(t-butoxycarbonylamino)ethyl)phenyl)(4-chlorophenyl)iodonium p-toluenesulfonate 
• 1382355-06-7 (2-(2-(benzyloxycarbonylamino)ethyl)phenyl)(4-chlorophenyl)iodonium p-toluenesulfonate 
• 1382355-16-9 (2-(2-acetamidoethyl)phenyl)(4-chlorophenyl)iodonium p-toluenesulfonate 
• 1382355-26-1 (2-(2-(3,3-diethylureido)ethyl)phenyl)(4-chlorophenyl)iodonium p-toluenesulfonate 
• 97899-38-2 (2-oxo-1,3-oxazolidin-5-yl)-methyl 4-methylbenzenesulfonate 
• 1428064-54-3 4-chlorophenyl(2,4-dimethoxyphenyl)iodonium tosylate 
• 1836-74-4 4-(4-chlorophenoxy)nitrobenzene 
• 2444-89-5 4,4'-dichlorodiphenyl ether 
• 7005-72-3 4-chlorodiphenyl ether 

Relevant articles and documents

Facile synthesis of Koser's reagent and derivatives from iodine or aryl iodides

The first one-pot synthesis of neutral and electron-rich [hydroxy(tosyloxy)iodo]arenes (HTIBs) from iodine and arenes is presented, thereby avoiding the need for expensive iodine(III) precursors. A large set of HTIBs, including a polyfluorinated analogue, can be obtained from the corresponding aryl iodide under the same conditions. The reaction proceeds under mild conditions, without excess reagents, and is fast and high-yielding. Together, the two presented routes give access to a wide range of HTIBs, which are useful reagents in a variety of synthetic transformations.

Approach to the synthesis of indoline derivatives from diaryliodonium salts

An effective method of constructing the indoline moiety via intramolecular nucleophilic ring closure of a diaryliodonium salt is described. Diacetoxyiodoarene compounds (1a-1e) were converted into intermediate Koser's reagent and coupled with arylstannanes (7-10) to form diaryliodonium salts (11a-14e). Indoline compounds with different N-protecting groups, 15, 16, 17, and 18, were synthesized in higher yields by treating salts (11a-14e) with Cs2CO3 and TEMPO. Regardless of the electronic environment of five para-substituted iodoarenes and the natures of four N-protected arylstannane groups, the conversion proceeded well to afford corresponding indolines in yields of 72-84 and 70-84%, respectively.

Facile one-pot preparation of [hydroxy(sulfonyloxy)iodo]arenes from iodoarenes with MCPBA in the presence of sulfonic acids

Various [hydroxy(sulfonyloxy)iodo]arenes were simply and efficiently obtained in high yields from the reaction of iodoarenes and MCPBA in the presence of sulfonic acids in a small amount of chloroform at room temperature, through a one-pot procedure. Georg Thieme Verlag Stuttgart.