73261-94-6

Upstream product

• 22483-09-6 2,2-dimethoxyethylamine 
• 456-48-4 3-Fluorobenzaldehyde 

Downstream Products

• 73261-77-5 N-(3-fluorobenzyl)-N-(2,2-dimethoxyethyl)acetamide 
• 630422-89-8 1-chloro-7-fluoroisoquinoline 
• 410086-27-0 7-fluoroisoquinoline-1(2H)-one 
• 1075-12-3 7-fluoroisoquinoline 
• 95333-80-5 1-(3-Fluoro-benzyl)-1,3-dihydro-imidazole-2-thione 
• 1099778-01-4 N-(2,2-dimethoxyethyl)-3-fluorobenzylamine hydrochloride 

Relevant academic research and scientific papers

ACTIVATORS OF AUTOPHAGIC FLUX AND PHOSPHOLIPASE D AND CLEARANCE OF PROTEIN AGGREGATES INCLUDING TAU AND TREATMENT OF PROTEINOPATHIES

The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.