1075-12-3 Usage
Uses
Used in Pharmaceutical Industry:
7-Fluoroisoquinoline is used as an active pharmaceutical ingredient for the development of drugs with antitumor, anti-inflammatory, and antimicrobial properties. Its unique chemical structure allows for the modulation of various biological pathways, making it a promising candidate for the treatment of various diseases and conditions.
Used in Agrochemical Industry:
7-Fluoroisoquinoline is used as a key intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its ability to interact with specific biological targets in pests and weeds makes it an effective component in the development of novel and efficient agrochemicals.
Used in Dye Industry:
7-Fluoroisoquinoline is used as a building block in the synthesis of dyes with specific color properties and stability. Its versatile reactivity allows for the creation of a wide range of dyes for various applications, including textiles, plastics, and printing inks.
Used in Organic Synthesis:
7-Fluoroisoquinoline is used as a versatile reagent and building block in organic synthesis for the preparation of various organic compounds. Its unique chemical properties enable the formation of a broad range of compounds with diverse applications in industries such as pharmaceuticals, agrochemicals, and materials science.
Used in Medicinal Chemistry Research:
7-Fluoroisoquinoline is used as a valuable research tool in medicinal chemistry for the investigation of its potential therapeutic applications. Its unique structure and reactivity allow researchers to explore its interactions with various biological targets, leading to the discovery of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1075-12-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,7 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1075-12:
(6*1)+(5*0)+(4*7)+(3*5)+(2*1)+(1*2)=53
53 % 10 = 3
So 1075-12-3 is a valid CAS Registry Number.
1075-12-3Relevant academic research and scientific papers
Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions
Pearson, Stuart E.,Fillery, Shaun M.,Goldberg, Kristin,Demeritt, Julie E.,Eden, Jonathan,Finlayson, Jonathan,Patel, Anil
, p. 4963 - 4981 (2018/12/13)
Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further derivatised. Synthesis of isoquinoline starting materials using several different methods is also described.
Method for synthesizing 4-bromo-7-fluoroisoquinoline
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Paragraph 0019; 0083-0084, (2018/08/03)
The invention provides a method for synthesizing 4-bromo-7-fluoroisoquinoline. The method is characterized in that 5-fluoro-2-methyl-benzoic acid is taken as a starting material and is subjected to areaction to generate 7-fluoroisoquinoline, and lastly the 7-fluoroisoquinoline is subjected to a bromination reaction to obtain the 4-bromo-7-fluoroisoquinoline. The method for synthesizing the 4-bromo-7-fluoroisoquinoline provided by the invention has the advantages of simple synthesizing route, reasonable process selection, low raw material cost, adoption of readily-available raw material, convenience in operation and posttreatment, high yield, no use of highly-toxic reagents, easiness in performing scale-up experiments, realization of large-scale production and the like.
ACTIVATORS OF AUTOPHAGIC FLUX AND PHOSPHOLIPASE D AND CLEARANCE OF PROTEIN AGGREGATES INCLUDING TAU AND TREATMENT OF PROTEINOPATHIES
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Paragraph 0054, (2017/05/07)
The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.
