1075-12-3

Basic information

• Product Name: 7-FLUOROISOQUINOLINE
• Synonyms: 7-FLUOROISOQUINOLINE
• CAS NO: 1075-12-3
• Molecular Formula: C9H6FN
• Molecular Weight: 147.15
• Mol File: 1075-12-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 7-FLUOROISOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-FLUOROISOQUINOLINE(1075-12-3)
• EPA Substance Registry System: 7-FLUOROISOQUINOLINE(1075-12-3)

Safety Data

• Hazardous Substances Data: 1075-12-3(Hazardous Substances Data)

Usage

General Description

7-Fluoroisoquinoline is a chemical compound which belongs to the class of isoquinoline compounds, a heterocyclic aromatic organic compound. It is mainly used in organic synthesis and medicinal chemistry for the production of pharmaceuticals, agrochemicals, and dyes. 7-FLUOROISOQUINOLINE has been studied for its potential applications in antitumor, anti-inflammatory, and antimicrobial activities. It is commonly used as a building block in the synthesis of other organic compounds due to its versatile reactivity. Its properties and potential applications make it an important chemical in various industries.

Upstream product

• 1481-32-9 6-fluoroindan-1-one 
• 52031-15-9 5-fluoro-1H-indene 
• 52085-94-6 6-fluoro-2,3-dihydro-1H-inden-1-ol 
• 630422-89-8 1-chloro-7-fluoroisoquinoline 
• 175278-28-1 5-fluoro-2-methylbenzamide 
• 33184-16-6 5-fluoro-2-methylbenzoic acid 
• 73261-94-6 N-<(3-fluorophenyl)methylene>-2,2-dimethoxyethanamine 
• 456-48-4 3-Fluorobenzaldehyde 

Downstream Products

• 410086-27-0 7-fluoroisoquinoline-1(2H)-one 
• 630422-89-8 1-chloro-7-fluoroisoquinoline 

Relevant articles and documents

Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions

Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further derivatised. Synthesis of isoquinoline starting materials using several different methods is also described.

ACTIVATORS OF AUTOPHAGIC FLUX AND PHOSPHOLIPASE D AND CLEARANCE OF PROTEIN AGGREGATES INCLUDING TAU AND TREATMENT OF PROTEINOPATHIES

The present application discloses compounds which are activators of autophagic flux and pharmaceutical compositions comprising said activators. It further discloses use of said compounds and pharmaceutical compositions in the treatment of neurodegenerative diseases, particularly proteinopathies and tauopathies such as Alzheimer's disease. It further discloses methods of enhancing autophagic flux.