73300-82-0Relevant academic research and scientific papers
Ruthenium-Catalyzed Alkylation of Cyclopropanols with Sulfoxonium Ylides via C-C Bond Cleavage: Formation of Diverse 1,5-Diketones
Huang, Xin,Li, Jianglian,He, Hua,Yan, Kaichuan,Lai, Ruizhi,Luo, Yi,Guan, Mei,Wu, Yong
, p. 779 - 787 (2021/10/29)
A novel ruthenium-catalyzed alkylation of cyclopropanols with sulfoxonium ylides has been developed that affords diverse 1,5-diketones with good efficiency and broad substrate scope. To illustrate the synthetic applications of the obtained 1,5-diketones, aldol and cyclization reactions have been investigated. Preliminary mechanistic studies suggest that this process involves a sequential C C activation and carbene migratory insertion.
Photoredox-Catalyzed Decarboxylative Alkylation of Silyl Enol Ethers to Synthesize Functionalized Aryl Alkyl Ketones
Kong, Weiguang,Yu, Changjiang,An, Hejun,Song, Qiuling
, p. 349 - 352 (2018/01/28)
Photoredox-catalyzed decarboxylative alkylation of silyl enol ethers has been developed. Diverse functionalized aryl alkyl ketones were afforded in modest to good yields using N-(acyloxy)phthalimide as an easy access alkyl radical source under mild and operationally simple conditions. The excellent performance of drug molecules such as fenbufen and indomethacin and naturally occurring carboxylic acids such as stearic acid and dehydrocholic acid further demonstrated the practicability of the reaction.
Photochemistry of 1,5-Diaryl-1,5-diketones
Bays, J. P.,Encinas, M. V.,Small, R. D.,Scaiano, J. C.
, p. 727 - 734 (2007/10/02)
The photochemistry of ketones 1-3 has been examined in solution at room temperature by using quantum yield and laser flash photolysis techniques.Triplet energy migration between the two chromophores leads to complete excitation equilibration.In the case of 3, two triplet states have been characterized, reflecting the syn and anti conformations of the o-methylbenzoyl chromophore.The biradicals produced in the triplet decay have lifetimes of ca. 50 ns in wet acetonitrile, for 1 and 2 and 430 ns in the case of 3, where it results from abstraction of the benzylic hydrogens.Biradicals are produced from 2 with a quantum yield of 1.0; however, the product yields are considerably lower, even in polar hydroxylic solvents.The effect is attributed to strong intramolecular hydrogen bonding in the biradical.
